The effect of neutropenia on the clinical pharmacokinetics of vancomycin in adults
Sign Up to like & getrecommendations! Published in 2019 at "European Journal of Clinical Pharmacology"
DOI: 10.1007/s00228-019-02657-6
Abstract: AimThere is accumulating evidence that neutropenic patients require higher dosages of vancomycin. To prevent sub-therapeutic drug exposure, it is of utmost importance to obtain adequate exposure from the first dose onwards. We aimed to quantify… read more here.
Keywords: effect neutropenia; volume distribution; patients known; pharmacokinetics vancomycin ... See more keywords
Comparative analysis of pharmacokinetics of vancomycin hydrochloride in rabbits after ocular, intragastric, and intravenous administration by LC-MS/MS
Sign Up to like & getrecommendations! Published in 2020 at "Xenobiotica"
DOI: 10.1080/00498254.2020.1774681
Abstract: Abstract The objective of this study was to compare the pharmacokinetics of vancomycin hydrochloride administered into rabbits through different routes and explore the feasibility of peptide drugs entering the systemic circulation through ocular administration. A… read more here.
Keywords: administration; pharmacokinetics vancomycin; intravenous administration; vancomycin hydrochloride ... See more keywords
Population Pharmacokinetics of Vancomycin in Pediatric Extracorporeal Membrane Oxygenation*
Sign Up to like & getrecommendations! Published in 2018 at "Pediatric Critical Care Medicine"
DOI: 10.1097/pcc.0000000000001682
Abstract: Objectives: Describe the pharmacokinetics of vancomycin in pediatric patients undergoing extracorporeal membrane oxygenation and provide dosing recommendations to attain an area under the curve for 24 hours greater than 400 in this population. Design: Retrospective,… read more here.
Keywords: extracorporeal membrane; membrane oxygenation; population; pharmacokinetics vancomycin ... See more keywords
P61 Population pharmacokinetics of vancomycin in chinese ICU neonates: initial dosage recommendations
Sign Up to like & getrecommendations! Published in 2019 at "Archives of Disease in Childhood"
DOI: 10.1136/archdischild-2019-esdppp.99
Abstract: The main goal of our study was to characterize the population pharmacokinetics of vancomycin in critically ill Chinese neonates to develop a pharmacokinetic model and investigate factors that have significant influences on the pharmacokinetics of… read more here.
Keywords: pharmacokinetics vancomycin; model; pharmacology; clearance ... See more keywords
Pharmacokinetics of Vancomycin among Patients with Chemotherapy-Associated Febrile Neutropenia: Which Would Be the Best Dosing to Obtain Appropriate Exposure?
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DOI: 10.3390/antibiotics11111523
Abstract: Previous research has determined that the required doses for treating febrile neutropenia with vancomycin are higher than the doses used conventionally. These recommendations have been made considering pharmacotherapeutic goals based on minimum concentration (Cmin) between… read more here.
Keywords: patients chemotherapy; pharmacokinetics vancomycin; febrile neutropenia; among patients ... See more keywords
Pharmacokinetics of Vancomycin Installation in Pleural Cavity—A Clinical Case with Animal Experiments
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DOI: 10.3390/app11146456
Abstract: (1) background: Postpneumonectomy empyema is often observed in patients after a complete pneumonectomy. The management of these cases can be challenging when the condition of patients is complicated by a bronchopleural fistula. A multidisciplinary approach… read more here.
Keywords: installation pleural; pharmacokinetics vancomycin; case; vancomycin installation ... See more keywords