Articles with "pharmacologic inhibition" as a keyword



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Pharmacologic Inhibition of Pain Response to Incomplete Vascular Occlusion Blunts Cardiovascular Preconditioning Response.

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Published in 2021 at "Cardiovascular toxicology"

DOI: 10.1007/s12012-021-09680-z

Abstract: Complete vascular occlusion to distant tissue prior to an ischemic cardiac event can provide significant cardioprotection via remote ischemic preconditioning (RIPC). Despite understanding its mechanistic basis, its translation to clinical practice has been unsuccessful, likely… read more here.

Keywords: response; preconditioning response; vascular occlusion; pharmacologic inhibition ... See more keywords
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Genetic or pharmacologic inhibition of EGFR ameliorates sepsis-induced AKI

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Published in 2017 at "Oncotarget"

DOI: 10.18632/oncotarget.21244

Abstract: Despite recent studies have demonstrated that the EGF receptor (EGFR) activation provided a renoprotective role during ischemic and folic acid-induced AKI, the role and regulation mechanism of EGFR in septic AKI remains unclear. Here, gefitinib,… read more here.

Keywords: egfr; genetic pharmacologic; induced aki; pharmacologic inhibition ... See more keywords
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Pharmacologic Inhibition of β-Catenin With Pyrvinium Inhibits Murine and Human Models of Wilms Tumor

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Published in 2017 at "Oncology Research"

DOI: 10.3727/096504017x14992942781895

Abstract: Wilms tumor (WT) is the most common renal malignancy in children and the fourth most common pediatric solid malignancy in the US. Although the mechanisms underlying the WT biology are complex, these tumors most often… read more here.

Keywords: inhibition catenin; catenin; pyrvinium inhibits; wilms tumor ... See more keywords