Emerging pharmacological approaches to promote neurogenesis from endogenous glial cells.
Sign Up to like & getrecommendations! Published in 2017 at "Biochemical pharmacology"
DOI: 10.1016/j.bcp.2017.06.129
Abstract: Neurodegenerative disorders are emerging as leading contributors to the global disease burden. While some drug-based approaches have been designed to limit or prevent neuronal loss following acute damage or chronic neurodegeneration, regeneration of functional neurons… read more here.
Keywords: neurogenesis endogenous; pharmacological approaches; approaches promote; glial cells ... See more keywords
Combinatorial Psycho-Pharmacological Approaches for the Treatment of Abnormal Aggression
Sign Up to like & getrecommendations! Published in 2018 at "Neuropsychopharmacology"
DOI: 10.1038/npp.2017.174
Abstract: Aggression is a highly evolutionarily adaptive behavior that is critical for survival and reproduction, and therefore, strongly ethologically conserved across species. However, due to environmental or biological processes, aggressive behavior can transition from adaptive to… read more here.
Keywords: violence; psycho pharmacological; pharmacological approaches; abnormal aggression ... See more keywords
New approved and emerging pharmacological approaches to alcohol use disorder: a review of clinical studies
Sign Up to like & getrecommendations! Published in 2021 at "Expert Opinion on Pharmacotherapy"
DOI: 10.1080/14656566.2021.1892641
Abstract: ABSTRACT Abstract introduction: The number of medications approved for AUD is small and they generally have limited efficacy. We need new pharmacotherapies for the management of AUD. Areas covered: In this review, the authors aim… read more here.
Keywords: pharmacological approaches; approaches alcohol; approved emerging; new approved ... See more keywords
Pharmacological approaches to treat intestinal pain
Sign Up to like & getrecommendations! Published in 2023 at "Expert Review of Clinical Pharmacology"
DOI: 10.1080/17512433.2023.2195626
Abstract: ABSTRACT Introduction Pain is one of the most substantial factors responsible for lowering quality of life in patients with intestinal diseases. Its multifactorial pathogenesis makes intestinal pain difficult to manage with currently available medications, especially… read more here.
Keywords: pharmacological approaches; intestinal pain; approaches treat; inflammatory ... See more keywords
Dietary Strategies and Novel Pharmaceutical Approaches Targeting Serum ApoA-I Metabolism: A Systematic Overview
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Nutrition and Metabolism"
DOI: 10.1155/2017/5415921
Abstract: The incidence of CHD is still increasing, which underscores the need for new preventive and therapeutic approaches to decrease CHD risk. In this respect, increasing apoA-I concentrations may be a promising approach, especially through increasing… read more here.
Keywords: pharmacological approaches; metabolism; metabolism systematic; apoa metabolism ... See more keywords
Pharmacological Approaches to Attenuate Inflammation and Obesity with Natural Products Formulations by Regulating the Associated Promoting Molecular Signaling Pathways
Sign Up to like & getrecommendations! Published in 2021 at "BioMed Research International"
DOI: 10.1155/2021/2521273
Abstract: Obesity is a public health problem characterized by increased body weight due to abnormal adipose tissue expansion. Bioactive compound consumption from the diet or intake of dietary supplements is one of the possible ways to… read more here.
Keywords: pharmacological approaches; obesity natural; natural products; inflammation ... See more keywords
Exploring pharmacological approaches for managing cytokine storm associated with pneumonia and acute respiratory distress syndrome in COVID-19 patients
Sign Up to like & getrecommendations! Published in 2020 at "Critical Care"
DOI: 10.1186/s13054-020-03020-3
Abstract: Sars-CoV-2 complications include pneumonia and acute respiratory distress syndrome (ARDS), which require intensive care unit admission. These conditions have rapidly overwhelmed healthcare systems, with detrimental effects on the quality of care and increased mortality. Social… read more here.
Keywords: pharmacological approaches; distress syndrome; pneumonia acute; cytokine storm ... See more keywords
Improvement on Hypertension Management with Pharmacological and Non-Pharmacological Approaches: Current Perspectives.
Sign Up to like & getrecommendations! Published in 2020 at "Current pharmaceutical design"
DOI: 10.2174/1381612826666200922153045
Abstract: PURPOSE Improving hypertension management is still one of the severest challenges in public health worldwide. Existing guidelines do not reach a consensus on the optimal Blood Pressure (BP) target. Therefore, how to effectively manage hypertension… read more here.
Keywords: pharmacological approaches; hypertension management; pharmacological non; hypertension ... See more keywords
Pharmacological approaches to the prevention of type 2 diabetes mellitus
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Endocrinology"
DOI: 10.3389/fendo.2023.1118848
Abstract: About 1 in 10 adults worldwide are estimated to have diabetes mellitus. They are at risk of developing life-threatening complications resulting in reduced quality of life, increased mortality and higher healthcare costs. The ability to… read more here.
Keywords: approaches prevention; pharmacological approaches; prevention type; type diabetes ... See more keywords
Pharmacological Approaches for the Modulation of the Potassium Channel KV4.x and KChIPs
Sign Up to like & getrecommendations! Published in 2021 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms22031419
Abstract: Ion channels are macromolecular complexes present in the plasma membrane and intracellular organelles of cells. Dysfunction of ion channels results in a group of disorders named channelopathies, which represent an extraordinary challenge for study and… read more here.
Keywords: modulation; potassium; pharmacological approaches; channel ... See more keywords
New Pharmacological Approaches for Rare Diseases
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24087275
Abstract: The expression "rare disease" describes a group of diseases whose individual prevalence is low (between 3.9 and 6.6 in 10,000 subjects depending on the country) but which in total affect up to the 3-6% of… read more here.
Keywords: new pharmacological; rare diseases; approaches rare; pharmacological approaches ... See more keywords