Articles with "pharmacological effect" as a keyword



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Assessment of Safety, Tolerability, Pharmacokinetics, and Pharmacological Effect of Orally Administered CORT125134: An Adaptive, Double‐Blind, Randomized, Placebo‐Controlled Phase 1 Clinical Study

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Published in 2018 at "Clinical Pharmacology in Drug Development"

DOI: 10.1002/cpdd.389

Abstract: CORT125134 is an orally active, high‐affinity, selective antagonist of the glucocorticoid receptor that is being developed for indications that may benefit from the modulation of cortisol activity. This first‐in‐human study was conducted to evaluate the… read more here.

Keywords: safety tolerability; pharmacological effect; study; tolerability pharmacokinetics ... See more keywords