Ex vivo culture of lesional psoriasis skin for pharmacological testing.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of dermatological science"
DOI: 10.1016/j.jdermsci.2019.12.010
Abstract: BACKGROUND Psoriasis is a chronic, inflammatory skin disorder resulting from a complex interplay between immune and skin cells via release of soluble mediators. While a lot is known about the molecular mechanisms behind psoriasis pathogenesis,… read more here.
Keywords: vivo culture; skin; psoriasis skin; psoriasis ... See more keywords
Pharmacological testing of therapeutics using Normothermic Machine Perfusion; a pilot study of 2,4-Dinitrophenol delivery to steatotic human livers.
Sign Up to like & getrecommendations! Published in 2022 at "Artificial organs"
DOI: 10.1111/aor.14309
Abstract: INTRODUCTION Normothermic machine perfusion (NMP) provides a platform for drug-delivery. However, pharmacological considerations for therapeutics delivered during NMP are scarcely reported. We aimed to demonstrate the ability of NMP as a platform for pharmacological testing,… read more here.
Keywords: normothermic machine; machine perfusion; pharmacological testing; drug ... See more keywords