Purinergic receptors modulators: An emerging pharmacological tool for disease management
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DOI: 10.1002/med.21888
Abstract: Purinergic signaling is mediated through extracellular nucleotides (adenosine 5′‐triphosphate, uridine‐5'‐triphosphate, adenosine diphosphate, uridine‐5'‐diphosphate, and adenosine) that serve as signaling molecules. In the early 1990s, purines and pyrimidine receptors were cloned and characterized drawing the attention… read more here.
Keywords: pharmacological tool; purinergic receptors; emerging pharmacological; modulators emerging ... See more keywords
Dissecting Actomyosin Mechanochemistry using Blebbistatin as a Pharmacological Tool
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DOI: 10.1016/j.bpj.2016.11.657
Abstract: Muscle contraction results from cyclic interactions between actin and myosin under turnover of ATP. Here, we use the myosin II-specific inhibitor blebbistatin as a pharmacological tool to elucidate this interaction. Particularly we consider the hypotheses… read more here.
Keywords: pharmacological tool; blebbistatin; muscle; blebbistatin pharmacological ... See more keywords
Ketamine as a pharmacological tool for the preclinical study of memory deficit in schizophrenia
Sign Up to like & getrecommendations! Published in 2022 at "Behavioural Pharmacology"
DOI: 10.1097/fbp.0000000000000689
Abstract: Schizophrenia is a serious neuropsychiatric disorder characterized by the presence of positive symptoms (hallucinations, delusions, and disorganization of thought and language), negative symptoms (abulia, alogia, and affective flattening), and cognitive impairment (attention deficit, impaired declarative… read more here.
Keywords: pharmacological tool; ketamine pharmacological; deficit; cognitive impairment ... See more keywords