Location of contact residues in pharmacologically distinct drug binding sites on P‐glycoprotein
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DOI: 10.1016/j.bcp.2016.10.002
Abstract: Graphical abstract Figure. No Caption available. Abstract The multidrug resistance P‐glycoprotein (P‐gp) is characterised by the ability to bind and/or transport an astonishing array of drugs. This poly‐specificity is imparted by at least four pharmacologically… read more here.
Keywords: drug binding; central cavity; contact residues; pharmacologically distinct ... See more keywords
Mediation of Sinusoidal Network Oscillations in the Locus Coeruleus of Newborn Rat Slices by Pharmacologically Distinct AMPA and KA Receptors
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DOI: 10.3390/brainsci12070945
Abstract: Brain control by locus coeruleus (LC) neurons involves afferent glutamate (Glu) inputs. In newborns, LC Glu receptors and responses may be sparse due to immaturity of the brain circuits providing such input. However, we reported,… read more here.
Keywords: network; locus coeruleus; brain; pharmacologically distinct ... See more keywords