Platelet Pharmacytes for the Hierarchical Amplification of Antitumor Immunity in Response to Self‐Generated Immune Signals
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DOI: 10.1002/adma.202109517
Abstract: Systemic immunosuppression mediated by tumor‐derived exosomes is an important cause for the resistance of immune checkpoint blockade (ICB) therapy. Herein, self‐adaptive platelet (PLT) pharmacytes are engineered to mediate cascaded delivery of exosome‐inhibiting siRNA and anti‐PD‐L1… read more here.
Keywords: pharmacytes hierarchical; antitumor; platelet pharmacytes; response ... See more keywords