Failed Progenitor Specification Underlies the Cardiopharyngeal Phenotypesin a Zebrafish Model of 22q11.2 Deletion Syndrome
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DOI: 10.1016/j.celrep.2018.06.117
Abstract: SUMMARY Microdeletions involving TBX1 result in variable congenital malformations known collectively as 22q11.2 deletion syndrome (22q11.2DS). Tbx1-deficient mice and zebrafish recapitulate several disease phenotypes, including pharyngeal arch artery (PAA), head muscle (HM), and cardiac outflow… read more here.
Keywords: deletion syndrome; pharyngeal arch; progenitor; specification ... See more keywords