LAUSR

About LAUSR
Donate
Contact Us

Follow us:

You are not signed in:

Sign Up!


   Articles with "phase" as a keyword



Photo from wikipedia

Rapid Development of an Integrated Network Infrastructure to Conduct Phase 3 COVID-19 Vaccine Trials.

Sign Up to like & get
recommendations! Published in 2023 at "JAMA network open"

DOI: 10.1001/jamanetworkopen.2022.51974

Abstract: Importance The COVID-19 pandemic has caused millions of infections and deaths and resulted in unprecedented international public health social and economic crises. As SARS-CoV-2 spread across the globe and its impact became evident, the development… read more here.

Keywords: vaccine trials; development; covid; phase ... See more keywords
Photo by nci from unsplash

Opicapone as Adjunct to Levodopa Therapy in Patients With Parkinson Disease and Motor Fluctuations: A Randomized Clinical Trial

Sign Up to like & get
recommendations! Published in 2017 at "JAMA Neurology"

DOI: 10.1001/jamaneurol.2016.4703

Abstract: Importance Catechol O-methyltransferase (COMT) inhibitors are an established treatment for end-of-dose motor fluctuations associated with levodopa therapy in patients with Parkinson disease (PD). Current COMT inhibitors carry a high risk for toxic effects to hepatic… read more here.

Keywords: phase; opicapone; treatment; time ... See more keywords
Photo by des0519 from unsplash

Alpelisib Plus Fulvestrant in PIK3CA-Altered and PIK3CA-Wild-Type Estrogen Receptor–Positive Advanced Breast Cancer: A Phase 1b Clinical Trial

Sign Up to like & get
recommendations! Published in 2018 at "JAMA Oncology"

DOI: 10.1001/jamaoncol.2018.4475

Abstract: Importance The phosphatidylinositol 3-kinase (PI3K) pathway is frequently activated in patients with estrogen receptor–positive (ER+), endocrine therapy–resistant breast cancers. Objective To assess the maximum tolerated dose (MTD), safety, and activity of alpelisib, an oral, PI3K&agr;-specific… read more here.

Keywords: phase; plus fulvestrant; pik3ca altered; wild type ... See more keywords
Photo from wikipedia

Assessment of Safety and Efficacy of Combined Trabectedin and Low-Dose Radiotherapy for Patients With Metastatic Soft-Tissue Sarcomas: A Nonrandomized Phase 1/2 Clinical Trial.

Sign Up to like & get
recommendations! Published in 2020 at "JAMA oncology"

DOI: 10.1001/jamaoncol.2019.6584

Abstract: Importance Active therapeutic combinations, such as trabectedin and radiotherapy, offer potentially higher dimensional response in second-line treatment of advanced soft-tissue sarcomas. Dimensional response can be relevant both for symptom relief and for survival. Objective To… read more here.

Keywords: phase; metastatic soft; soft tissue; radiotherapy ... See more keywords
Photo from wikipedia

Activity of Cabazitaxel in Metastatic or Inoperable Locally Advanced Dedifferentiated Liposarcoma: A Phase 2 Study of the EORTC Soft Tissue and Bone Sarcoma Group (STBSG).

Sign Up to like & get
recommendations! Published in 2022 at "JAMA oncology"

DOI: 10.1001/jamaoncol.2022.3218

Abstract: Importance Treatment options for patients with unresectable and/or metastatic dedifferentiated liposarcoma (DDLPS) are limited. New drugs are required. Objective To assess whether cabazitaxel demonstrated sufficient antitumor activity in patients with metastatic or inoperable locally advanced… read more here.

Keywords: locally advanced; metastatic inoperable; dedifferentiated liposarcoma; activity ... See more keywords
Photo from wikipedia

Treatment With Stereotactic Ablative Radiotherapy for Up to 5 Oligometastases in Patients With Cancer: Primary Toxic Effect Results of the Nonrandomized Phase 2 SABR-5 Clinical Trial.

Sign Up to like & get
recommendations! Published in 2022 at "JAMA oncology"

DOI: 10.1001/jamaoncol.2022.4394

Abstract: Importance After the publication of the landmark SABR-COMET trial, concerns arose regarding high-grade toxic effects of treatment with stereotactic ablative body radiotherapy (SABR) for oligometastases. Objective To document toxic effects of treatment with SABR in… read more here.

Keywords: sabr; trial; phase; toxic effects ... See more keywords
Photo from wikipedia

Evaluation of Artificial Intelligence-Based Intraoperative Guidance Tools for Phacoemulsification Cataract Surgery.

Sign Up to like & get
recommendations! Published in 2022 at "JAMA ophthalmology"

DOI: 10.1001/jamaophthalmol.2021.5742

Abstract: Importance Complications that arise from phacoemulsification procedures can lead to worse visual outcomes. Real-time image processing with artificial intelligence tools can extract data to deliver surgical guidance, potentially enhancing the surgical environment. Objective To evaluate… read more here.

Keywords: phacoemulsification cataract; cataract; surgery; guidance ... See more keywords
Photo from wikipedia

Targeting Cognition and Networks Through Neural Oscillations: Next-Generation Clinical Brain Stimulation.

Sign Up to like & get
recommendations! Published in 2019 at "JAMA psychiatry"

DOI: 10.1001/jamapsychiatry.2019.0740

Abstract: Mental disorders often involve difficulty with complex cognitive functions, such as decision making, emotional self-regulation, or behavioral adaptation to changing circumstances. Those functions arise from the carefully timed and orchestrated synchrony of activity across multiple… read more here.

Keywords: phase; stimulation; gamma activity; activity ... See more keywords
Photo from wikipedia

Phase relationship between ULF waves and drift-bounce resonant ions: a statistical study†

Sign Up to like & get
recommendations! Published in 2017 at "Journal of Geophysical Research"

DOI: 10.1002/2016ja023848

Abstract: We explore the phase relationship between the poloidal mode ULF wave electric field oscillations and drift-bounce resonant oxygen ions under the resonant condition of N=2 at the magnetic equator. Using Cluster data from 2001 to… read more here.

Keywords: phase; bounce resonant; drift bounce; resonant ions ... See more keywords
Photo from wikipedia

Using large eddy simulations to reveal the size, strength, and phase of updraft and downdraft cores of an Arctic mixed phase stratocumulus cloud†

Sign Up to like & get
recommendations! Published in 2017 at "Journal of Geophysical Research"

DOI: 10.1002/2016jd026055

Abstract: Three-dimensional large eddy simulations (LES) are used to analyze a springtime Arctic mixed-phase stratocumulus observed on 26 April 2008 during the Indirect and Semi-Direct Aerosol Campaign (ISDAC). Two subgrid-scale turbulence parameterizations are compared. The first… read more here.

Keywords: phase; arctic mixed; phase stratocumulus; cloud ... See more keywords
Photo by heytowner from unsplash

Trajectories toward the 1.5°C Paris target: Modulation by the Interdecadal Pacific Oscillation

Sign Up to like & get
recommendations! Published in 2017 at "Geophysical Research Letters"

DOI: 10.1002/2017gl073480

Abstract: Global temperature is rapidly approaching the 1.5°C Paris target. In the absence of external cooling influences, such as volcanic eruptions, temperature projections are centered on a breaching of the 1.5°C target, relative to 1850–1900, before… read more here.

Keywords: phase; temperature; paris target; interdecadal pacific ... See more keywords