Articles with "phase crossover" as a keyword



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A Single Supratherapeutic Dose of Atogepant Does Not Affect Cardiac Repolarization in Healthy Adults: Results From a Randomized, Single‐Dose, Phase 1 Crossover Trial

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Published in 2021 at "Clinical Pharmacology in Drug Development"

DOI: 10.1002/cpdd.940

Abstract: Atogepant is a selective, oral calcitonin gene–related peptide receptor antagonist in development for preventive treatment of migraine. This randomized, double‐blind, phase 1 crossover study evaluated the cardiac repolarization effect of a single supratherapeutic (300 mg)… read more here.

Keywords: dose atogepant; cardiac repolarization; time; phase crossover ... See more keywords