Single-Cell RNA-Sequencing Analyses Revealed Heterogeneity and Dynamic Changes of Metabolic Pathways in Astrocytes at the Acute Phase of Ischemic Stroke
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DOI: 10.1155/2022/1817721
Abstract: Astrocyte plays important roles in the pathogenesis of ischemic stroke and reperfusion injury. They intensively participate in the energy metabolism of the brain, while their heterogeneity and function after ischemic stroke remain controversial. By employing… read more here.
Keywords: acute phase; astrocytes acute; single cell; phase ischemic ... See more keywords
Microglial Calcium Waves During the Hyperacute Phase of Ischemic Stroke
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DOI: 10.1161/strokeaha.120.032766
Abstract: Supplemental Digital Content is available in the text. Background and Purpose: Ischemic injury triggers multiple pathological responses in the brain tissue, including spreading depolarizations across the cerebral cortex (cortical spreading depolarizations [CSD]). Microglia have been… read more here.
Keywords: ischemic stroke; microglial calcium; calcium transients; calcium ... See more keywords