Articles with "phase kinetics" as a keyword



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An HPLC-UV validated bioanalytical method for measurement of in vitro phase 1 kinetics of α-synuclein binding bifunctional compounds

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Published in 2022 at "Xenobiotica"

DOI: 10.1080/00498254.2022.2140315

Abstract: Abstract Aggregates of the protein α-synuclein are associated with pathophysiology of Parkinson’s disease and are present in Lewy Bodies found in the brains of Parkinson’s patients. We previously demonstrated that bifunctional compounds composed of caffeine… read more here.

Keywords: pet probes; phase; vitro phase; phase kinetics ... See more keywords