Campylobacter phages use hypermutable polyG tracts to create phenotypic diversity and evade bacterial resistance.
Sign Up to like & getrecommendations! Published in 2021 at "Cell reports"
DOI: 10.1016/j.celrep.2021.109214
Abstract: Phase variation is a common mechanism for creating phenotypic heterogeneity of surface structures in bacteria important for niche adaptation. In Campylobacter, phase variation occurs by random variation in hypermutable homonucleotide 7-11 G (polyG) tracts. To elucidate… read more here.
Keywords: polyg tracts; phase; hypermutable polyg; phase variable ... See more keywords
Phase-variable capsular polysaccharides and lipoproteins modify bacteriophage susceptibility in Bacteroides thetaiotaomicron
Sign Up to like & getrecommendations! Published in 2020 at "Nature microbiology"
DOI: 10.1038/s41564-020-0746-5
Abstract: A variety of cell surface structures dictate interactions between bacteria and their environment, including their viruses (bacteriophages). Members of the human gut Bacteroidetes characteristically produce several phase-variable capsular polysaccharides (CPSs), but their contributions to bacteriophage… read more here.
Keywords: polysaccharides lipoproteins; phase; variable capsular; bacteroides thetaiotaomicron ... See more keywords
Non-typeable Haemophilus influenzae isolates from patients with chronic obstructive pulmonary disease contain new phase-variable modA methyltransferase alleles controlling phasevarions
Sign Up to like & getrecommendations! Published in 2019 at "Scientific Reports"
DOI: 10.1038/s41598-019-52429-6
Abstract: Phasevarions (phase-variable regulons) are emerging as an important area of bacterial gene regulation. Many bacterial pathogens contain phasevarions, with gene expression controlled by the phase-variable expression of DNA methyltransferases via epigenetic mechanisms. Non-typeable Haemophilus influenzae… read more here.
Keywords: haemophilus influenzae; non typeable; phase variable; typeable haemophilus ... See more keywords
A Griffiths-like phase and variable range hopping of polarons in orthorhombic perovskite Pr2CrMnO6
Sign Up to like & getrecommendations! Published in 2019 at "New Journal of Chemistry"
DOI: 10.1039/c9nj04059e
Abstract: Orthorhombic Pr2CrMnO6synthesized by the Pechini method establishes a way to exploring the charge, lattice and spin degrees of freedom in praseodymium based perovskites. read more here.
Keywords: griffiths like; like phase; variable range; range hopping ... See more keywords
Actinobacillus pleuropneumoniae encodes multiple phase-variable DNA methyltransferases that control distinct phasevarions
Sign Up to like & getrecommendations! Published in 2022 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkad091
Abstract: Actinobacillus pleuropneumoniae is the cause of porcine pleuropneumonia, a severe respiratory tract infection that is responsible for major economic losses to the swine industry. Many host-adapted bacterial pathogens encode systems known as phasevarions (phase- variable… read more here.
Keywords: dna; type iii; actinobacillus pleuropneumoniae; phase ... See more keywords
Phage exposure causes dynamic shifts in the expression states of specific phase-variable genes of Campylobacter jejuni.
Sign Up to like & getrecommendations! Published in 2017 at "Microbiology"
DOI: 10.1099/mic.0.000470
Abstract: Phase variation (PV) creates phenotypic heterogeneity at high frequencies and in a reversible manner. This phenomenon allows bacteria to adapt to a variety of different environments and selective pressures. In Campylobacterjejuni this reversible adaptive process… read more here.
Keywords: phase; phage f336; phage; exposure ... See more keywords
A Feasibility Study of Piecewise Phase Variable Based on Variable Toe-Off for the Powered Prosthesis Control: A Case Study
Sign Up to like & getrecommendations! Published in 2023 at "IEEE Robotics and Automation Letters"
DOI: 10.1109/lra.2023.3256927
Abstract: Achieving stable walking and proper assistance in prosthesis control requires synchronized control, treating the user and the prosthesis as a coupled system. Furthermore, speed adaptability is essential for controlling the prosthesis at different walking speeds.… read more here.
Keywords: toe; prosthesis control; prosthesis; phase ... See more keywords
A Phase Variable Approach for IMU-Based Locomotion Activity Recognition
Sign Up to like & getrecommendations! Published in 2018 at "IEEE Transactions on Biomedical Engineering"
DOI: 10.1109/tbme.2017.2750139
Abstract: Objective: This paper describes a gait classification method that utilizes measured motion of the thigh segment provided by an inertial measurement unit. Methods: The classification method employs a phase-variable description of gait, and identifies a… read more here.
Keywords: classification method; classification; activity; phase variable ... See more keywords
Analysis of Invasive Nontypeable Haemophilus influenzae Isolates Reveals Selection for the Expression State of Particular Phase-Variable Lipooligosaccharide Biosynthetic Genes
Sign Up to like & getrecommendations! Published in 2019 at "Infection and Immunity"
DOI: 10.1128/iai.00093-19
Abstract: Nontypeable Haemophilus influenzae (NTHi) is a major human pathogen, responsible for several acute and chronic infections of the respiratory tract. The incidence of invasive infections caused by NTHi is increasing worldwide. ABSTRACT Nontypeable Haemophilus influenzae… read more here.
Keywords: expression; nontypeable haemophilus; phase variable; haemophilus influenzae ... See more keywords
Phase-variable Type I methyltransferase M.NgoAV from Neisseria gonorrhoeae FA1090 regulates phasevarion expression and gonococcal phenotype
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2022.917639
Abstract: The restriction-modification (RM) systems are compared to a primitive, innate, prokaryotic immune system, controlling the invasion by foreign DNA, composed of methyltransferase (MTase) and restriction endonuclease. The biological significance of RM systems extends beyond their… read more here.
Keywords: phenotype; neisseria gonorrhoeae; expression; type ... See more keywords
Campylobacter jejuni Developed the Resistance to Bacteriophage CP39 by Phase Variable Expression of 06875 Encoding the CGPTase
Sign Up to like & getrecommendations! Published in 2022 at "Viruses"
DOI: 10.3390/v14030485
Abstract: Bacteriophage (phage) is regarded as an antimicrobial alternative for Campylobacter in food production. However, the development of phage resistance to the host is a main concern for the phage application. This study characterized the phage… read more here.
Keywords: variable expression; cp39; phage cp39; resistance ... See more keywords