L-carnitine alleviates cardiac microvascular dysfunction in diabetic cardiomyopathy by enhancing PINK1-Parkin-dependent mitophagy through the CPT1a-PHB2-PARL pathways.
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DOI: 10.1111/apha.13975
Abstract: AIM To explore the beneficial effects of L-carnitine on cardiac microvascular dysfunction in diabetic cardiomyopathy from the perspectives of mitophagy and mitochondrial integrity. METHODS Male db/db and db/m mice were randomly assigned to groups and… read more here.
Keywords: cardiac microvascular; parl; cpt1a; mitophagy ... See more keywords