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1
Published in 2017 at "Journal of Molecular Modeling"
DOI: 10.1007/s00894-017-3248-5
Abstract: AbstractComplexes of the dipeptide phenylalanine–phenylalanine (Phe–Phe) with divalent metal cations (Cu2+, Zn2+, Ca2+ and Ba2+) were studied at the B3LYP and MP2 levels of theory with the basis sets 6-311++G(d,p) and 6-31 + G(d) in…
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Keywords:
zn2 ca2;
phe phe;
ca2 ba2;
phe ... See more keywords
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0
Published in 2018 at "ACS chemical neuroscience"
DOI: 10.1021/acschemneuro.8b00218
Abstract: The melanocortin-3 and melanocortin-4 receptors (MC3R and MC4R), endogenous agonists derived from the proopiomelanocortin gene transcript, and naturally occurring antagonists agouti and agouti-related protein (AGRP) have been linked to biological pathways associated with energy homeostasis.…
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Keywords:
xxx;
arg phe;
phe phe;
antagonist ... See more keywords
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2
Published in 2022 at "ACS Omega"
DOI: 10.1021/acsomega.2c06351
Abstract: The crystal structure of l-phenylalanyl l-phenylalanine (Phe-Phe, FF, a.k.a. diphenylalanine) is not merely noncentrosymmetric, but it is highly dipole parallel aligned. It is for this reason that FF is a nonlinear optical (NLO) material and…
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Keywords:
phe;
synthesis;
importance solvent;
phe phe ... See more keywords
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Published in 2017 at "Chemical communications"
DOI: 10.1039/c7cc04106c
Abstract: Synthetic control of peptide-based supramolecular assemblies can provide molecular cues to understand protein aggregation while also inspiring the development of novel chemical biology tools to deliver cargoes inside cells. Here we show that the trans-to-cis…
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Keywords:
modulating phe;
phe phe;
phe dipeptide;
phe ... See more keywords
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Published in 2022 at "Drug and chemical toxicology"
DOI: 10.1080/01480545.2022.2118315
Abstract: The diagnosis and treatment of the diseases in a certain coordination is a subject that has been emphasized in recent years. Theragnostics approaches allow simultaneous diagnosis and treatment of chronic diseases such as cancer. An…
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Keywords:
non;
phe;
dna damage;
phe dipeptides ... See more keywords
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Published in 2017 at "Journal of Virology"
DOI: 10.1128/jvi.01026-17
Abstract: ABSTRACT The inhibitors carbobenzoxy (Z)-d-Phe-l-Phe-Gly (fusion inhibitor peptide [FIP]) and 4-nitro-2-phenylacetyl amino-benzamide (AS-48) have similar efficacies in blocking membrane fusion and syncytium formation mediated by measles virus (MeV). Other homologues, such as Z-d-Phe, are less…
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Keywords:
protein;
phe phe;
membrane fusion;
fusion ... See more keywords
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Published in 2021 at "Journal of biomedical nanotechnology"
DOI: 10.1166/jbn.2021.3022
Abstract: Ferulic acid (FA), an active component extracted from Chinese medicine, shows excellent anti-inflammatory properties and favorable safety in various animal models. However, the application of FA as an anti-inflammatory drug is hindered by its instability…
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Keywords:
phe nanoparticles;
treatment;
phe phe;
pegylated phe ... See more keywords
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Published in 2022 at "Protein and peptide letters"
DOI: 10.2174/0929866529666220530085836
Abstract: BACKGROUND The fight against cancer has started since the dawn of their discovery and has not subsided to nowadays. Currently, the hybrid molecules become a promising alternative to the standard chemotherapeutics for treatment of multi-causal…
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Keywords:
hydrolytic stability;
cell;
phe;
thr ... See more keywords
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Published in 2019 at "Applied Sciences"
DOI: 10.3390/app9132601
Abstract: L-phenylseptin (L-Phes) and D-phenylseptin (D-Phes) are amphibian antimicrobial peptides isolated from the skin secretion of Hypsiboas punctatus. In the N-termini, L-Phes and D-Phes contain three consecutive phenylalanine residues, l-Phe-l-Phe-l-Phe and l-Phe-d-Phe-l-Phe, respectively. They are known…
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Keywords:
dimyristoyl glycero;
antimicrobial peptides;
study interactions;
glycero phosphocholine ... See more keywords
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1
Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23137173
Abstract: Short peptides have great potential as safe and effective anticancer drug leads. Herein, the influence of short cyclic peptides containing the Pro-Pro-Phe-Phe sequence on patient-derived melanoma cells was investigated. Cyclic peptides such as cyclo(Leu-Ile-Ile-Leu-Val-Pro-Pro-Phe-Phe-), called…
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Keywords:
phe;
melanoma cells;
cyclo pro;
phe phe ... See more keywords
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Published in 2019 at "Molecules"
DOI: 10.3390/molecules24244460
Abstract: Morphine, which acts through opioid receptors, is one of the most efficient analgesics for the alleviation of severe pain. However, its usefulness is limited by serious side effects, including analgesic tolerance, constipation, and dependence liability.…
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Keywords:
phe phe;
nk1 antagonist;
pharmacological evaluation;
neurokinin ... See more keywords