Synthesis and Anticancer Activity Evaluation of Novel Phenanthridine Derivatives
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2019.00274
Abstract: Based on the structure of sanguinarine, fourteen phenanthridine derivatives were designed and synthesized in the current study. The cytotoxic activities of synthesized compounds were evaluated against five human cancer cell lines (MCF-7, PC3, Hela, A549,… read more here.
Keywords: synthesis anticancer; anticancer activity; phenanthridine derivatives; cell ... See more keywords
Phenanthridine derivatives as promising new anticancer agents: synthesis, biological evaluation and binding studies.
Sign Up to like & getrecommendations! Published in 2020 at "Future medicinal chemistry"
DOI: 10.4155/fmc-2019-0016
Abstract: Aim: Phenanthridines are an essential class of nitrogenous heterocycles with extensive applications in medicinal chemistry. The development of efficient and eco-friendly methods for the preparation of chirally pure dihydropyrrolo[1,2-f]phenanthridines (5a-h), and their in vitro evaluation… read more here.
Keywords: promising new; chemistry; evaluation; phenanthridine derivatives ... See more keywords