Design, synthesis, and antiproliferative effect of 2,9‐bis[4‐(pyridinylalkylaminomethyl)phenyl]‐1,10‐phenanthroline derivatives on human leukemic cells by targeting G‐quadruplex
Sign Up to like & getrecommendations! Published in 2021 at "Archiv der Pharmazie"
DOI: 10.1002/ardp.202000450
Abstract: Current multiagent chemotherapy regimens have improved the cure rate in acute leukemia patients, but they are highly toxic and poorly efficient in relapsed patients. To improve the treatment approaches, new specific molecules are needed. The… read more here.
Keywords: phenyl phenanthroline; phenanthroline derivatives; bis; design synthesis ... See more keywords
Antibacterial activities and DNA-cleavage properties of novel fluorescent imidazo-phenanthroline derivatives.
Sign Up to like & getrecommendations! Published in 2020 at "Bioorganic chemistry"
DOI: 10.1016/j.bioorg.2020.103885
Abstract: Design and biological activities of fluorescent imidazo-phenanthroline derivatives; (E)-5-((4-((4-(1H-imidazo[4,5-f][1,10]phenanthrolin-2-yl)phenoxy)methyl)benzylidene)amino)- isophthalicacid, 2 and 2-(4-(((5-chloroquinolin-8-yl)oxy)methyl)phenyl)-1H-imidazo[4,5f] [1,10]phenanthroline, 3, have been reported. Their characterizations were performed by spectroscopic techniques. Their promising photophysical behaviours were observed in absorbance and fluorescence… read more here.
Keywords: phenanthroline derivatives; fluorescent imidazo; imidazo phenanthroline; phenanthroline ... See more keywords
[AuIII(N^N)Br2](PF6): A Class of Antibacterial and Antibiofilm Complexes (N^N = 2,2′-Bipyridine and 1,10-Phenanthroline Derivatives)
Sign Up to like & getrecommendations! Published in 2023 at "Inorganic Chemistry"
DOI: 10.1021/acs.inorgchem.2c04410
Abstract: A series of new complexes of general formula [AuIII(N^N)Br2](PF6) (N^N = 2,2′-bipyridine and 1,10-phenanthroline derivatives) were prepared and characterized by spectroscopic, electrochemical, and diffractometric techniques and tested against Gram-positive and Gram-negative bacterial strains (Staphylococcus aureus,… read more here.
Keywords: bipyridine phenanthroline; auiii br2; antibacterial antibiofilm; br2 pf6 ... See more keywords
Intramolecular electron transfer in Cu(ii) complexes with aryl-imidazo-1,10-phenanthroline derivatives: experimental and quantum chemical calculation studies
Sign Up to like & getrecommendations! Published in 2019 at "New Journal of Chemistry"
DOI: 10.1039/c8nj05697h
Abstract: First observation of Cu(ii)–Cu(i) autoreduction in complex with aryl-imidazo-1,10-phenanthroline derivatives. read more here.
Keywords: phenanthroline derivatives; aryl imidazo; imidazo phenanthroline; intramolecular electron ... See more keywords
An expeditious synthesis of 6,7-dihydrodibenzo[b,j][4,7] phenanthroline derivatives as fluorescent materials
Sign Up to like & getrecommendations! Published in 2022 at "RSC Advances"
DOI: 10.1039/d2ra05198b
Abstract: A rapid and efficient method has been developed for the synthesis of 13,14-dimethyl-6,7-dihydrodibenzo[b,j][4,7]phenanthroline derivatives (3a–d) through the Friedländer condensation of 2-aminoarylketone with 1,4-cyclohexanedione under solvent-free conditions using p-toluenesulphonic acid. The synthetic utility of compounds 3a,… read more here.
Keywords: synthesis; dihydrodibenzo phenanthroline; 160 160; 120 120 ... See more keywords
Synthesis and antiplasmodial activity of novel phenanthroline derivatives: An in vivo study
Sign Up to like & getrecommendations! Published in 2018 at "Iranian Journal of Basic Medical Sciences"
DOI: 10.22038/ijbms.2017.24558.6106
Abstract: Objective(s): Due to the rapid increased drug resistance to Plasmodium parasites, an urgent need to achieve new antiplasmodial drugs is felt. Therefore, in this study, the new synthetic phenanthroline derivatives were synthesized with antiplasmodial activity.… read more here.
Keywords: phenanthroline derivatives; synthetic compounds; antiplasmodial activity; study ... See more keywords