A genetic screen in combination with biochemical analysis in Saccharomyces cerevisiae indicates that phenazine-1-carboxylic acid is harmful to vesicular trafficking and autophagy
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DOI: 10.1038/s41598-017-01452-6
Abstract: The environmentally friendly antibiotic phenazine-1-carboxylic acid (PCA) protects plants, mammals and humans effectively against various fungal pathogens. However, the mechanism by which PCA inhibits or kills fungal pathogens is not fully understood. We analyzed the… read more here.
Keywords: vesicular trafficking; saccharomyces cerevisiae; phenazine carboxylic; carboxylic acid ... See more keywords
Synthesis and fungicidal activity of 1,3,4-oxadiazol-2-yl thioether derivatives containing a phenazine-1-carboxylic acid scaffold
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DOI: 10.1080/14786419.2018.1489389
Abstract: Abstract To find new higher fungicidal activities lead compounds and develop new eco-friendly agrochemicals, natural product phenazine-1-carboxylic acid (PCA) as scaffold, a series of 1,3,4-oxadiazol-2-yl thioether derivatives was synthesized and bio-assayed. The results reveal that… read more here.
Keywords: thioether derivatives; phenazine carboxylic; carboxylic acid; oxadiazol thioether ... See more keywords
Sensitivity of Rhizoctonia Isolates to Phenazine-1-Carboxylic Acid and Biological Control by Phenazine-Producing Pseudomonas spp.
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DOI: 10.1094/phyto-07-16-0257-r
Abstract: Rhizoctonia solani anastomosis groups (AG)-8 and AG-2-1 and R. oryzae are ubiquitous in cereal-based cropping systems of the Columbia Plateau of the Inland Pacific Northwest and commonly infect wheat. AG-8 and R. oryzae, causal agents… read more here.
Keywords: precipitation; phenazine carboxylic; rhizoctonia; phz pseudomonads ... See more keywords
The Effect of Phenazine-1-Carboxylic Acid on Mycelial Growth of Botrytis cinerea Produced by Pseudomonas aeruginosa LV Strain
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DOI: 10.3389/fmicb.2017.01102
Abstract: One of the most important postharvest plant pathogens that affect strawberries, grapes and tomatoes is Botrytis cinerea, known as gray mold. The fungus remains in latent form until spore germination conditions are good, making infection… read more here.
Keywords: pseudomonas aeruginosa; microscopy; phenazine carboxylic; carboxylic acid ... See more keywords
Synthesis, Crystal Structure and Bioactivity of Phenazine-1-carboxylic Acylhydrazone Derivatives
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DOI: 10.3390/molecules26175320
Abstract: A phenazine-1-carboxylic acid intermediate was synthesized from the reaction of aniline and 2-bromo-3-nitro-benzoic acid. It was then esterified and reacted with hydrazine hydrate to afford phenazine-1-carboxylic hydrazine. Finally, 10 new hydrazone compounds 3a–3j were obtained… read more here.
Keywords: crystal structure; structure bioactivity; phenazine; phenazine carboxylic ... See more keywords