Repeated phencyclidine disrupts nicotinic acetylcholine regulation of dopamine release in nucleus accumbens: Implications for models of schizophrenia
Sign Up to like & getrecommendations! Published in 2020 at "Neurochemistry International"
DOI: 10.1016/j.neuint.2020.104836
Abstract: Dopaminergic dysregulation in nucleus accumbens has been implicated in the origin of schizophrenia. Accumbal cholinergic interneurons exert powerful modulatory control of local dopamine function, through nicotinic receptors located on dopamine terminals. Fast-scan cyclic voltammetry in… read more here.
Keywords: phencyclidine; dopamine release; dopamine; release ... See more keywords
Pseudo-Wellens’ syndrome secondary to concurrent cannabis and phencyclidine intoxication
Sign Up to like & getrecommendations! Published in 2018 at "BMJ Case Reports"
DOI: 10.1136/bcr-2018-225755
Abstract: Wellens’ syndrome is an electrocardiographic pattern of T-wave changes associated with critical stenosis of the proximal left anterior descending artery, signifying imminent risk of an anterior-wall myocardial infarction. The Wellens’ electrocardiographic pattern can also be… read more here.
Keywords: phencyclidine; cannabis; wellens syndrome; intoxication ... See more keywords
Novel ketamine analogues cause a false positive phencyclidine immunoassay
Sign Up to like & getrecommendations! Published in 2019 at "Annals of Clinical Biochemistry"
DOI: 10.1177/0004563219858125
Abstract: Background Immunoassays are commonly used to test for drugs of abuse in patients in a variety of settings. The increasing prevalence of ‘designer’ drugs causes difficulties for the toxicology laboratory and may result in unexpected… read more here.
Keywords: phencyclidine; phencyclidine immunoassay; ketamine; false positive ... See more keywords
Global brain volume reductions in a sub-chronic phencyclidine animal model for schizophrenia and their relationship to recognition memory
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Psychopharmacology"
DOI: 10.1177/0269881119844196
Abstract: Background: Cognitive deficits and structural brain changes co-occur in patients with schizophrenia. Improving our understanding of the relationship between these is important to develop improved therapeutic strategies. Back-translation of these findings into rodent models for… read more here.
Keywords: phencyclidine; brain volume; chronic phencyclidine; sub chronic ... See more keywords