GYF-21, an epoxide 2‑(2‑phenethyl)‑chromone derivative, suppresses dysfunction of B cells mainly via inhibiting BAFF activated signaling pathways.
Sign Up to like & getrecommendations! Published in 2019 at "International immunopharmacology"
DOI: 10.1016/j.intimp.2018.12.048
Abstract: Activated B cells targeted to autoantigens proliferate and differentiate into antibody-secreting cells. Overproduced autoantibodies will give rise to autoimmune diseases. In this study, we investigated the inhibitory effects of GYF-21, an epoxide 2‑(2‑phenethyl)‑chromone derivative extracted… read more here.
Keywords: epoxide phenethyl; phenethyl chromone; autoimmune diseases; chromone derivative ... See more keywords
Two new 2-(2-phenethyl)chromone derivatives from agarwood of Aquilaria walla and their cytotoxicity
Sign Up to like & getrecommendations! Published in 2021 at "Phytochemistry Letters"
DOI: 10.1016/j.phytol.2021.01.010
Abstract: Abstract Two new 2-(2-phenethyl)chromone derivatives were isolated from agarwood of Aquilaria walla, including a dimeric 2-(2-phenethyl)chromone (1) and a flavonoid-2-(2-phenethyl)chromone (2). Their structures were established based on spectroscopic methods including HRESIMS, 1D, and 2D NMR.… read more here.
Keywords: two new; phenethyl chromone; agarwood aquilaria; new phenethyl ... See more keywords