Anti-rheumatic activity of Phenethyl isothiocyanate via inhibition of histone deacetylase-1.
Sign Up to like & getrecommendations! Published in 2020 at "Chemico-biological interactions"
DOI: 10.1016/j.cbi.2020.109095
Abstract: Rheumatoid Arthritis (RA) affects approximately 1% of the total world population. Despite incessant research and development of new therapeutic agents, management of RA is still a troublesome affair. Histone Deacetylase 1 (HDAC1) is an epigenetic… read more here.
Keywords: phenethyl isothiocyanate; isothiocyanate; activity phenethyl; histone deacetylase ... See more keywords
Type 2 diabetes mellitus potentiates acute acrylonitrile toxicity: Potentiation reduction by phenethyl isothiocyanate.
Sign Up to like & getrecommendations! Published in 2021 at "Toxicology and industrial health"
DOI: 10.1177/07482337211048583
Abstract: Acrylonitrile (AN) is a known animal carcinogen and suspected human carcinogen. Recently, occupational exposure to AN has considerably increased. Previously, we demonstrated that streptozotocin-induced diabetes potentiates AN-induced acute toxicity in rats and that the induced… read more here.
Keywords: acute toxicity; toxicity; phenethyl isothiocyanate; type ... See more keywords
Phenethyl isothiocyanate protects against cyclophosphamide-induced nephrotoxicity via nuclear factor E2–related factor 2 pathway in rats
Sign Up to like & getrecommendations! Published in 2023 at "Experimental Biology and Medicine"
DOI: 10.1177/15353702221139206
Abstract: Phenethyl isothiocyanate (PEITC), a secondary metabolite in Cruciferous plants, exerts chemopreventive and antioxidant effects. However, its therapeutic potential in cyclophosphamide (CP)-induced nephrotoxicity is not clear. So, we focused to research on the effect of PEITC… read more here.
Keywords: nuclear factor; phenethyl isothiocyanate; factor; cyclophosphamide induced ... See more keywords
Dietary Phenethyl Isothiocyanate Protects Mice from Colitis Associated Colon Cancer
Sign Up to like & getrecommendations! Published in 2017 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms18091908
Abstract: We have previously reported alleviation of dextran sodium sulfate (DSS)-induced ulcerative colitis signs in phenethyl isothiocyanate (PEITC)-treated mice. Here we investigated chemoprotective activities of PEITC in mice with Azoxymethane-DSS induced colitis associated colon carcinogenesis. We… read more here.
Keywords: colon; phenethyl isothiocyanate; colitis; associated colon ... See more keywords