Novel Potent ABCB1 Modulator, Phenethylisoquinoline Alkaloid, Reverses Multidrug Resistance in Cancer Cell.
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DOI: 10.1021/acs.molpharmaceut.8b00457
Abstract: ATP-binding cassette (ABC) transporters, which are concerned with the efflux of anticancer drugs from cancer cells, have a pivotal role in multidrug resistance (MDR). In particular, ABCB1 is a well-known ABC transporter that develops MDR… read more here.
Keywords: resistance; phenethylisoquinoline alkaloid; cancer; abcb1 ... See more keywords