One-Step Regioselective Synthesis of Benzofurans from Phenols and α-Haloketones
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DOI: 10.3390/molecules24112187
Abstract: Reported here is the direct synthesis of naphthofurans and benzofurans from readily available phenols and α-haloketones promoted by titanium tetrachloride which combines Friedel–Crafts-like alkylation and intramolecular cyclodehydration into one step. This simple protocol allows for… read more here.
Keywords: regioselective synthesis; step regioselective; one step; phenols haloketones ... See more keywords