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Published in 2019 at "European Journal of Organic Chemistry"
DOI: 10.1002/ejoc.201801689
Abstract: The continuous flow synthesis of a model phenothiazine antipsychotic is presented herein, using 3-chloropropionyl chloride as a central building block. The basic phenothiazine-derived scaffold is (atom)-efficiently and mildly synthesized with the aim to present continuous…
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Keywords:
flow synthesis;
phenothiazine;
continuous flow;
phenothiazine antipsychotics ... See more keywords
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Published in 2023 at "Antibiotics"
DOI: 10.3390/antibiotics12010137
Abstract: Multidrug resistance (MDR) is a major obstacle in the therapy of infectious diseases and cancer. One of the major mechanisms of MDR is the overexpression of efflux pumps (EPs) that are responsible for extruding antimicrobial…
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Keywords:
infectious diseases;
phenothiazine antipsychotics;
development;
repurposing antidepressants ... See more keywords