The renal phenotype of allopurinol-treated HPRT-deficient mouse
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DOI: 10.1371/journal.pone.0173512
Abstract: Excess of uric acid is mainly treated with xanthine oxidase (XO) inhibitors, also called uricostatics because they block the conversion of hypoxanthine and xanthine into urate. Normally, accumulation of upstream metabolites is prevented by the… read more here.
Keywords: hprt; xanthine; phenotype allopurinol; renal phenotype ... See more keywords