G × G × E effect on phenotype expression in a non-conventional model organism, the unicellular slime mould Physarum polycephalum
Sign Up to like & getrecommendations! Published in 2023 at "Biology Letters"
DOI: 10.1098/rsbl.2022.0494
Abstract: In metazoans, the expression of key phenotypic traits is sensitive to two- and three-way interactions between variation in mitochondrial DNA, nuclear DNA and the external environment. Whether gene-by-environment interactions affect phenotypes in single-celled eukaryotes is… read more here.
Keywords: phenotype expression; slime mould; unicellular slime; mould physarum ... See more keywords
Cohort Analysis of 67 Charcot-Marie-Tooth Italian Patients: Identification of New Mutations and Broadening of Phenotype Expression Produced by Rare Variants
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2021.682050
Abstract: Charcot-Marie-Tooth (CMT) disease is the most prevalent inherited motor sensory neuropathy, which clusters a clinically and genetically heterogeneous group of disorders with more than 90 genes associated with different phenotypes. The goal of this study… read more here.
Keywords: genetics; charcot marie; rare variants; broadening phenotype ... See more keywords