Inhibition of DNA methylation in newborns reprograms ischemia-sensitive biomarkers resulting in development of a heart ischemia-sensitive phenotype late in life.
Sign Up to like & getrecommendations! Published in 2021 at "Reproductive toxicology"
DOI: 10.1016/j.reprotox.2021.09.007
Abstract: Adverse environmental stress exposure at critical perinatal stages can alter cardiovascular development, which could persist into adulthood and develop a cardiovascular dysfunctional phenotype late in life. However, the underlying molecular mechanisms remain largely unknown. The… read more here.
Keywords: ischemia sensitive; late life; phenotype late; dna methylation ... See more keywords
Epileptic phenotype in late-onset hyperinsulinemic hypoglycemia successfully treated by diazoxide
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Pediatric Endocrinology and Metabolism"
DOI: 10.1515/jpem-2020-0381
Abstract: Abstract Objectives Serious hyperinsulinemic hypoglycemia (HH) is generally the main initial symptom of hyperinsulinism. Epilepsy, without any overt feature of hypoglycemia, might be a very rare initial presentation of late-onset isolated hyperinsulinism. Case presentation We… read more here.
Keywords: late onset; hypoglycemia; epileptic phenotype; phenotype late ... See more keywords