Blockade of programmed cell death protein 1 (PD-1) in Sézary syndrome reduces Th2 phenotype of non-tumoral T lymphocytes but may enhance tumor proliferation
Sign Up to like & getrecommendations! Published in 2020 at "Oncoimmunology"
DOI: 10.1080/2162402x.2020.1738797
Abstract: ABSTRACT Sézary syndrome (SS) is an aggressive leukemic variant of cutaneous T-cell lymphoma (L-CTCL) that arises from malignant clonally derived skin-homing CD4+ T cells. Based on advancements in our understanding of the mechanisms underlying L-CTCL,… read more here.
Keywords: zary syndrome; th2 phenotype; phenotype non; cell ... See more keywords
Abstract WP167: Is There a Distinct Phenotype for Non-Asian Moyamoya Patients?
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DOI: 10.1161/str.50.suppl_1.wp167
Abstract: Background and Purpose: Idiopathic moyamoya syndrome (IMMS) is a progressive narrowing of the anterior circulation arteries resulting in the development of a tenuous collateral blood supply which i... read more here.
Keywords: non asian; asian moyamoya; wp167 distinct; phenotype non ... See more keywords
De Novo Heterozygous GATA3 Missense Variant Causes an Unexpected Phenotype of Non-Syndromic Hearing Impairment with Apparently Recessive Inheritance
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DOI: 10.3390/ijms26136363
Abstract: Hearing impairments (HIs) are clinically and genetically very heterogeneous. Finding the causative mutations in patients is frequently a challenge. We investigated two brothers affected by a sensorineural, moderate non-syndromic HI. Exome sequencing revealed that they… read more here.
Keywords: unexpected phenotype; variant; non syndromic; gata3 ... See more keywords