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Published in 2017 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2017.10.122
Abstract: This study investigated the change of transient receptor potential cation channel subfamily M member 7 (TRPM7) expression in rat aortic vascular smooth muscle cells (RAoSMCs) treated with a high concentration of d-glucose (HG) and its…
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Keywords:
phenotype;
high concentration;
concentration glucose;
phenotype switching ... See more keywords
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Published in 2020 at "Placenta"
DOI: 10.1016/j.placenta.2020.02.017
Abstract: INTRODUCTION Establishment of hemochorial placenta is associated with development and remodelling of uterine vasculature at the maternal fetal interface. This results in calibration of high resistance uterine arteries to flaccid low resistance vessels resulting in…
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Keywords:
trophoblast cells;
vascular smooth;
phenotype switching;
smooth muscle ... See more keywords
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Published in 2022 at "Circulation Research"
DOI: 10.1161/circresaha.122.321080
Abstract: Rationale: Vascular smooth muscle cells (VSMCs) phenotype switch from contractile to proliferative phenotype is a pathological hallmark in various cardiovascular diseases. Recently, a subset of long noncoding RNAs was identified to produce functional polypeptides. However,…
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Keywords:
vsmc;
phenotype switching;
vascular remodeling;
psr ... See more keywords
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Published in 2022 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2022.930250
Abstract: Melanoma is a complex and aggressive cancer type that contains different cell subpopulations displaying distinct phenotypes within the same tumor. Metabolic reprogramming, a hallmark of cell transformation, is essential for melanoma cells to adopt different…
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Keywords:
cell;
melanoma;
phenotype switching;
rewiring phenotype ... See more keywords
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Published in 2022 at "Frontiers in Cardiovascular Medicine"
DOI: 10.3389/fcvm.2022.913039
Abstract: N6-methylatidine (m6A) is involved in post-transcriptional metabolism and a variety of pathological processes. However, little is known about the role of m6A in vascular proliferative diseases, particularly in vascular smooth muscle cells (VSMCs) phenotype switching-induced…
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Keywords:
muscle cells;
phenotype switching;
vascular smooth;
m6a ... See more keywords
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Published in 2020 at "Cancers"
DOI: 10.3390/cancers12082154
Abstract: Transcription factors, extensively described for their role in epithelial–mesenchymal transition (EMT-TFs) in epithelial cells, also display essential functions in the melanocyte lineage. Recent evidence has shown specific expression patterns and functions of these EMT-TFs in…
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Keywords:
transcription factors;
phenotype switching;
resistance treatment;