A deep convolutional neural network approach for predicting phenotypes from genotypes
Sign Up to like & getrecommendations! Published in 2018 at "Planta"
DOI: 10.1007/s00425-018-2976-9
Abstract: Main conclusionDeep learning is a promising technology to accurately select individuals with high phenotypic values based on genotypic data.AbstractGenomic selection (GS) is a promising breeding strategy by which the phenotypes of plant individuals are usually… read more here.
Keywords: deep convolutional; convolutional neural; phenotypes genotypes; approach ... See more keywords
Evaluation of phenotypes and genotypes of airborne Fungi during middle eastern dust storms
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Environmental Health Science and Engineering"
DOI: 10.1007/s40201-019-00428-0
Abstract: Microbial species such as bacteria and fungi can be transported by dust storms over long distances, and may change the mycobiota in downwind. This study aimed to evaluate phenotypes and genotypes of airborne fungi during… read more here.
Keywords: fungi middle; genotypes airborne; phenotypes genotypes; dust ... See more keywords
MMAP: a cloud computing platform for mining the maximum accuracy of predicting phenotypes from genotypes
Sign Up to like & getrecommendations! Published in 2021 at "Bioinformatics"
DOI: 10.1093/bioinformatics/btaa824
Abstract: Abstract Accurately predicting phenotypes from genotypes holds great promise to improve health management in humans and animals, and breeding efficiency in animals and plants. Although many prediction methods have been developed, the optimal method… read more here.
Keywords: computing platform; predicting phenotypes; platform mining; cloud computing ... See more keywords
The Monarch Initiative: an integrative data and analytic platform connecting phenotypes to genotypes across species
Sign Up to like & getrecommendations! Published in 2017 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkw1128
Abstract: The correlation of phenotypic outcomes with genetic variation and environmental factors is a core pursuit in biology and biomedicine. Numerous challenges impede our progress: patient phenotypes may not match known diseases, candidate variants may be… read more here.
Keywords: initiative integrative; across species; phenotypes genotypes; integrative data ... See more keywords
Linking Phenotypes and Genotypes with Matrix Factorizations.
Sign Up to like & getrecommendations! Published in 2023 at "Current pharmaceutical biotechnology"
DOI: 10.2174/1389201024666230207153738
Abstract: AIMS We propose a unified computational framework, PheGe-Net, to bridge phenotypes and genotypes. BACKGROUND Genotype is the genetic makeup of a cell, an organism, or an individual, usually regarding a specific characteristic under consideration. Phenotype… read more here.
Keywords: phege net; phenotype; phenotype genotype; genotype ... See more keywords
Phenotypes and Genotypes of Inherited Disorders of Biogenic Amine Neurotransmitter Metabolism
Sign Up to like & getrecommendations! Published in 2023 at "Genes"
DOI: 10.3390/genes14020263
Abstract: Inherited disorders of biogenic amine metabolism are genetically determined conditions resulting in dysfunctions or lack of enzymes involved in the synthesis, degradation, or transport of dopamine, serotonin, adrenaline/noradrenaline, and their metabolites or defects of their… read more here.
Keywords: metabolism; biogenic amine; disorders biogenic; genotypes inherited ... See more keywords
Phenotypes and Genotypes in Patients with SMC1A-Related Developmental and Epileptic Encephalopathy
Sign Up to like & getrecommendations! Published in 2023 at "Genes"
DOI: 10.3390/genes14040852
Abstract: The X-linked SMC1A gene encodes a core subunit of the cohesin complex that plays a pivotal role in genome organization and gene regulation. Pathogenic variants in SMC1A are often dominant-negative and cause Cornelia de Lange… read more here.
Keywords: epileptic encephalopathy; developmental epileptic; phenotypes genotypes; smc1a variants ... See more keywords
[Phenotypes and genotypes of 78 patients with propionic acidemia].
Sign Up to like & getrecommendations! Published in 2022 at "Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine]"
DOI: 10.3760/cma.j.cn112150-20220620-00630
Abstract: Objective: Propionic acidemia is a rare inherited metabolic disorder caused by propionyl CoA carboxylase (PCC) deficiency. This study aims to analyze the clinical characteristics and gene variations of Chinese patients with propionic acidemia, and to… read more here.
Keywords: onset; acidemia; phenotypes genotypes; patients propionic ... See more keywords