Articles with "phenotypic analysis" as a keyword



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Phenotypic Analysis and Molecular Markers of Plant Nodule Senescence.

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Published in 2018 at "Methods in molecular biology"

DOI: 10.1007/978-1-4939-7672-0_5

Abstract: Leguminous crops can form nodules to fix atmospheric nitrogen (N2). Senescence of nodules is associated with a rapid decline in N fixation. During the process of nodule senescence, a number of visible or detectable changes… read more here.

Keywords: senescence; phenotypic analysis; molecular markers; nodule senescence ... See more keywords
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A comprehensive and comparative phenotypic analysis of the collaborative founder strains identifies new and known phenotypes

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Published in 2020 at "Mammalian Genome"

DOI: 10.1007/s00335-020-09827-3

Abstract: The collaborative cross (CC) is a large panel of mouse-inbred lines derived from eight founder strains (NOD/ShiLtJ, NZO/HILtJ, A/J, C57BL/6J, 129S1/SvImJ, CAST/EiJ, PWK/PhJ, and WSB/EiJ). Here, we performed a comprehensive and comparative phenotyping screening to… read more here.

Keywords: founder; phenotypic analysis; comparative phenotypic; comprehensive comparative ... See more keywords
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Genetic and phenotypic analysis of carbohydrate metabolism and transport in Lactobacillus reuteri.

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Published in 2018 at "International journal of food microbiology"

DOI: 10.1016/j.ijfoodmicro.2018.02.021

Abstract: Lactobacilli derive metabolic energy mainly from carbohydrate fermentation. Homofermentative and heterofermentative lactobacilli exhibit characteristic differences in carbohydrate transport and regulation of metabolism, however, enzymes for carbohydrate transport in heterofermentative lactobacilli are poorly characterized. This study… read more here.

Keywords: metabolism; phenotypic analysis; transport; carbohydrate metabolism ... See more keywords
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Genomic and phenotypic analysis of Vavilov’s historic landraces reveals the impact of environment and genomic islands of agronomic traits

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Published in 2017 at "Scientific Reports"

DOI: 10.1038/s41598-017-05087-5

Abstract: The Vavilov Institute of Plant Genetic Resources (VIR), in St. Petersburg, Russia, houses a unique genebank, with historical collections of landraces. When they were collected, the geographical distribution and genetic diversity of most crops closely… read more here.

Keywords: phenotypic; historic landraces; genomic phenotypic; phenotypic analysis ... See more keywords
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Phenotypic analysis of catastrophic childhood epilepsy genes

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Published in 2021 at "Communications Biology"

DOI: 10.1038/s42003-021-02221-y

Abstract: Genetic engineering techniques have contributed to the now widespread use of zebrafish to investigate gene function, but zebrafish-based human disease studies, and particularly for neurological disorders, are limited. Here we used CRISPR-Cas9 to generate 40… read more here.

Keywords: epilepsy; childhood; zebrafish lines; analysis ... See more keywords
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Automated lipid droplet quantification system for phenotypic analysis of adipocytes using CellProfiler

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Published in 2020 at "Toxicology Mechanisms and Methods"

DOI: 10.1080/15376516.2020.1747124

Abstract: Abstract Adipogenic differentiation is the process by which preadipocytes become mature adipocytes, cells that store energy and regulate metabolic homeostasis. During differentiation, neutral lipids that accumulate in adipocytes can be detected using stains and used… read more here.

Keywords: phenotypic analysis; using cellprofiler; analysis; lipid droplet ... See more keywords
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Phenotypic Analysis of Human Lymph Nodes in Subjects With New-Onset Type 1 Diabetes and Healthy Individuals by Flow Cytometry

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Published in 2019 at "Frontiers in Immunology"

DOI: 10.3389/fimmu.2019.02547

Abstract: Background: Ultrasound guided sampling of human lymph node (LN) combined with advanced flow cytometry allows phenotypic analysis of multiple immune cell subsets. These may provide insights into immune processes and responses to immunotherapies not apparent… read more here.

Keywords: human lymph; analysis; phenotypic analysis; blood ... See more keywords
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The Natural History of CNGB1-Related Retinopathy: A Longitudinal Phenotypic Analysis

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Published in 2022 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms23126785

Abstract: Cyclic nucleotide-gated channel β 1 (CNGB1) encodes a subunit of the rod cyclic nucleotide-gated channel. Pathogenic variants in CNGB1 are responsible for 4% of autosomal recessive retinitis pigmentosa (RP). Several treatment strategies show promise for… read more here.

Keywords: natural history; cngb1 related; longitudinal phenotypic; history cngb1 ... See more keywords
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Transcriptomics and Phenotypic Analysis of gpr56 Knockout in Zebrafish

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Published in 2023 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms24097740

Abstract: The adhesion G-protein-coupled receptor is a seven-transmembrane receptor protein with a complex structure. Impaired GPR56 has been found to cause developmental damage to the human brain, resulting in intellectual disability and motor dysfunction. To date,… read more here.

Keywords: transcriptomics phenotypic; phenotypic analysis; gpr56 knockout; knockout zebrafish ... See more keywords