Generating A Database of Phenotypic Consequences of Gene Regulation Across 40 Human Tissues
Sign Up to like & getrecommendations! Published in 2017 at "European Neuropsychopharmacology"
DOI: 10.1016/j.euroneuro.2016.09.466
Abstract: Abstract GWAS and sequencing studies have yielded thousands of genetic variants robustly associated genetic complex traits. However, the underlying biology of those associations needs to be further elucidated. To address this problem we developed PrediXcan,… read more here.
Keywords: phenotypic consequences; human tissues; consequences gene; gene ... See more keywords
Characterization of the phenotypic consequences of the Duffy-null genotype
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DOI: 10.1182/bloodadvances.2024014399
Abstract: Key Points • rs2814778-CC is only reproducibly associated with changes in white blood cell count and not with any disease outcomes.• Race is not an accurate predictor of Duffy-null–associated benign neutropenia; genetic screening of rs2814778… read more here.
Keywords: characterization phenotypic; consequences duffy; null genotype; phenotypic consequences ... See more keywords