Involvement of c‐Jun N‐Terminal Kinase in TNF‐&agr;‐Driven Remodeling
Sign Up to like & getrecommendations! Published in 2017 at "American Journal of Respiratory Cell and Molecular Biology"
DOI: 10.1165/rcmb.2015-0195oc
Abstract: &NA; Lung tissue remodeling in chronic obstructive pulmonary disease (COPD) is characterized by airway wall thickening and/or emphysema. Although the bronchial and alveolar compartments are functionally independent entities, we recently showed comparable alterations in matrix… read more here.
Keywords: tnf; jnk; jun terminal; tnf agr ... See more keywords
Single-cell transcriptomics reveals skewed cellular communication and phenotypic shift in pulmonary artery remodeling
Sign Up to like & getrecommendations! Published in 2022 at "JCI Insight"
DOI: 10.1172/jci.insight.153471
Abstract: A central feature of progressive vascular remodeling is altered smooth muscle cell (SMC) homeostasis; however, the understanding of how different cell populations contribute to this process is limited. Here, we utilized single-cell RNA sequencing to… read more here.
Keywords: cell; single cell; communication; phenotypic shift ... See more keywords