Multivariate Control of Transcript to Protein Variability in Single Mammalian Cells.
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DOI: 10.1016/j.cels.2018.09.001
Abstract: A long-standing question in quantitative biology is the relationship between mRNA and protein levels of the same gene. Here, we measured mRNA and protein abundance, the phenotypic state, and the population context in thousands of… read more here.
Keywords: cell; mrna protein; protein abundance; phenotypic state ... See more keywords
The phenotypic state of biallelic SERPINA1 Q0 variants in α1-antitrypsin deficiency
Sign Up to like & getrecommendations! Published in 2025 at "ERJ Open Research"
DOI: 10.1183/23120541.00228-2025
Abstract: Extract Rare variants play an important role in α1-antitrypsin deficiency (AATD) [1]. The Mediterranean area has a high variability for rare pathogenic variants, more frequently reported in Morocco, Portugal, Italy, Cyprus and Greece [1–4.] Among… read more here.
Keywords: serpina1 variants; biallelic serpina1; antitrypsin deficiency; serpina1 ... See more keywords