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Phenotypic subtypes predict outcomes in colorectal cancer

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2 Published in 2023 at "Acta Oncologica"

DOI: 10.1080/0284186x.2023.2183779

Abstract: Abstract Background Colorectal cancer (CRC) is the second leading cause of cancer-related deaths globally. The Colorectal Cancer Subtyping Consortium used the transcriptome-based method to classify CRC according to four molecular subtypes, each showing different genomic… read more here.

Keywords: crc; colorectal cancer; phenotypic subtypes; subtype ... See more keywords

Abstract 4615: Phenotypic subtypes successfully stratify prognosis of patient with colorectal cancer: A step towards precision medicine

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0 Published in 2018 at "Cancer Research"

DOI: 10.1158/1538-7445.am2018-4615

Abstract: Background: There has been enormous effort to develop a prognostic genomic classification of colorectal cancer (CRC). As a result, mismatch repair (MMR) status was established as a prognostic marker in addition to TNM-staging. Phenotypic subtypes… read more here.

Keywords: medicine; colorectal cancer; mmr status; cancer ... See more keywords

Phenotypic subtypes as a novel validated prognostic classification system for patients with colorectal cancer.

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0 Published in 2018 at "Journal of Clinical Oncology"

DOI: 10.1200/jco.2018.36.4_suppl.625

Abstract: 625Background: There has been enormous effort to develop a prognostic genomic classification of colorectal cancer (CRC). As a result, mismatch repair (MMR) status was established as a prognostic marker in addition to TNM-staging. Phenotypic subtypes… read more here.

Keywords: classification; phenotypic; colorectal cancer; cohort ... See more keywords

Multi-Habitat Radiomics Unravels Distinct Phenotypic Subtypes of Glioblastoma with Clinical and Genomic Significance

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0 Published in 2020 at "Cancers"

DOI: 10.3390/cancers12071707

Abstract: We aimed to evaluate the potential of radiomics as an imaging biomarker for glioblastoma (GBM) patients and explore the molecular rationale behind radiomics using a radio-genomics approach. A total of 144 primary GBM patients were… read more here.

Keywords: multi habitat; phenotypic; gbm patients; habitat radiomics ... See more keywords

Metal Homeostasis and Exposure in Distinct Phenotypic Subtypes of Insulin Resistance among Children with Obesity

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2 Published in 2023 at "Nutrients"

DOI: 10.3390/nu15102347

Abstract: Background: Trace elements and heavy metals have proven pivotal roles in childhood obesity and insulin resistance. However, growing evidence suggests that insulin resistance could encompass distinct phenotypic subtypes. Methods: Herein, we performed a comprehensive metallomics… read more here.

Keywords: distinct phenotypic; insulin resistance; phenotypic subtypes; obesity ... See more keywords