Association of phenotypic transformation of circulating tumor cells and early recurrence in patients with hepatocellular carcinoma following liver transplantation.
Sign Up to like & getrecommendations! Published in 2021 at "Asian journal of surgery"
DOI: 10.1016/j.asjsur.2021.07.058
Abstract: BACKGROUND CTCs play a critical role in the diagnosis and prognosis of liver cancer. However, there are few studies on whether different types of CTCs can predict the prognosis in patients with HCC following LT.… read more here.
Keywords: phenotypic transformation; recurrence; transformation circulating; association phenotypic ... See more keywords
Hypoxia-Induced Phenotypic Transformation of Corpus Cavernosum Smooth Muscle Cells After Cavernous Nerve Crush Injury by Down-Regulating P38 Mitogen-Activated Protein Kinase Expression
Sign Up to like & getrecommendations! Published in 2019 at "Sexual Medicine"
DOI: 10.1016/j.esxm.2019.08.005
Abstract: Introduction Cavernosal nerve (CN) injury is commonly caused by radical prostatectomy surgery, and it might directly lead to erectile dysfunction (ED). Currently, the role of mitogen-activated protein kinase (MAPK) family proteins in phenotypic transformation of… read more here.
Keywords: phenotypic transformation; group; smooth muscle; hypoxia ... See more keywords
ETAR silencing ameliorated neurovascular injury after SAH in rats through ERK/KLF4-mediated phenotypic transformation of smooth muscle cells
Sign Up to like & getrecommendations! Published in 2021 at "Experimental Neurology"
DOI: 10.1016/j.expneurol.2021.113596
Abstract: Subarachnoid haemorrhage (SAH) is a devastating cerebrovascular disease which has a high morbidity and mortality. The phenotypic transformation of smooth muscle cells (SMCs) lead to neurovascular injury after SAH. However, the underlying mechanism remains unclear.… read more here.
Keywords: phenotypic transformation; neurovascular injury; transformation smcs; transformation ... See more keywords
Paired box 9 regulates VSMC phenotypic transformation, proliferation, and migration via sonic hedgehog.
Sign Up to like & getrecommendations! Published in 2020 at "Life sciences"
DOI: 10.1016/j.lfs.2020.118053
Abstract: AIMS Vascular smooth muscle cells (VSMCs) play a crucial role in the progression of atherosclerosis. Paired box 9 (Pax9) is a member of the Pax gene family which participates in the development of various tissues… read more here.
Keywords: proliferation migration; phenotypic transformation; transformation proliferation; proliferation ... See more keywords
Bmal1 inhibits phenotypic transformation of hepatic stellate cells in liver fibrosis via IDH1/α-KG-mediated glycolysis.
Sign Up to like & getrecommendations! Published in 2021 at "Acta pharmacologica Sinica"
DOI: 10.1038/s41401-021-00658-9
Abstract: Hepatic stellate cells (HSCs) play an important role in the initiation and development of liver fibrogenesis, and abnormal glucose metabolism is increasingly being considered a crucial factor controlling phenotypic transformation in HSCs. However, the role… read more here.
Keywords: phenotypic transformation; bmal1; glycolysis; liver fibrosis ... See more keywords
Fibronectin type III domain containing 5 attenuates NLRP3 inflammasome activation and phenotypic transformation of adventitial fibroblasts in spontaneously hypertensive rats
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Hypertension"
DOI: 10.1097/hjh.0000000000001654
Abstract: Objective: Phenotypic transformation of adventitial fibroblasts is important in the pathogenesis of hypertension. This study was designed to determine whether fibronectin type III domain containing 5 (FNDC5) alleviates the phenotypic transformation of adventitial fibroblasts in… read more here.
Keywords: phenotypic transformation; inflammasome activation; adventitial fibroblasts; transformation adventitial ... See more keywords
Microrna-29a Involvement in Phenotypic Transformation of Venous Smooth Muscle Cells via Tet1 in Response to Mechanical Cyclic Stretch.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of biomechanical engineering"
DOI: 10.1115/1.4044581
Abstract: Mechanical stimuli play an important role in vein graft restenosis and the abnormal migration and proliferation of vascular smooth muscle cells (VSMCs) are pathological processes contributing to this disorder. Here, based on previous high throughput… read more here.
Keywords: phenotypic transformation; stretch; mir 29a; smooth muscle ... See more keywords
Atorvastatin regulates vascular smooth muscle cell phenotypic transformation by epigenetically modulating contractile proteins and mediating Akt/FOXO4 axis.
Sign Up to like & getrecommendations! Published in 2022 at "Molecular medicine reports"
DOI: 10.3892/mmr.2022.12683
Abstract: Atherosclerosis (AS) is a prevalent cardiovascular disease with severe morbidity and high mortality. Phenotypic regulation of vascular smooth muscle cells (VSMCs) from the contractile and quiescent phenotype to the synthetic type is a critical step… read more here.
Keywords: contractile proteins; phenotypic transformation; phenotypic; atorvastatin ... See more keywords