Transdiagnostic Phenotyping Reveals a Host of Metacognitive Deficits Implicated in Compulsivity
Sign Up to like & getrecommendations! Published in 2020 at "Scientific Reports"
DOI: 10.1038/s41598-020-59646-4
Abstract: Recent work suggests that obsessive-compulsive disorder (OCD) patients have a breakdown in the relationship between explicit beliefs (i.e. confidence about states) and updates to behaviour. The precise computations underlying this disconnection are unclear because case-control… read more here.
Keywords: reveals host; confidence; phenotyping reveals; transdiagnostic phenotyping ... See more keywords
Deep phenotyping reveals movement phenotypes in mouse neurodevelopmental models
Sign Up to like & getrecommendations! Published in 2022 at "Molecular Autism"
DOI: 10.1186/s13229-022-00492-8
Abstract: Background Repetitive action, resistance to environmental change and fine motor disruptions are hallmarks of autism spectrum disorder (ASD) and other neurodevelopmental disorders, and vary considerably from individual to individual. In animal models, conventional behavioral phenotyping… read more here.
Keywords: reveals movement; cntnap2 knockouts; deep phenotyping; phenotyping reveals ... See more keywords