Photoactivation of Boronic Acid Prodrugs via a Phenyl Radical Mechanism: Iridium(III) Anticancer Complex as an Example.
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DOI: 10.1021/jacs.3c00254
Abstract: Boronic acid (or ester) is a well-known temporary masking group for developing anticancer prodrugs responsive to tumoral reactive oxygen species (ROS), but their clinic application is largely hampered by the low activation efficiency. Herein, we… read more here.
Keywords: phenyl radical; iridium iii; photoactivation; boronic acid ... See more keywords