Synthesis of 3-arylamino-6-phenyl[1, 2, 4]triazolo[3,4-b][1, 3, 4]thiadiazine derivatives as potential bioactive molecules
Sign Up to like & getrecommendations! Published in 2017 at "Chemistry of Heterocyclic Compounds"
DOI: 10.1007/s10593-017-2098-5
Abstract: 4-Amino-3-arylamino-5-mercapto-1,2,4-triazoles have been used as synthons for the synthesis of fused ring system of 3-arylamino-6-phenyl[1, 2, 4]triazolo[3,4-b][1, 3, 4]thiadiazines. The reaction in high yield produces compounds with bridgehead nitrogen and two separate hydrazine units in… read more here.
Keywords: phenyl triazolo; arylamino phenyl; arylamino; synthesis ... See more keywords
One-Pot, Multi-Component Synthesis of Substituted 2-(6-Phenyl-7H-[1,2,4]Triazolo[3,4-b][1,3,4]Thiadiazin-3-yl)-2,3-Dihydrophthalazine-1,4-Diones
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DOI: 10.1080/10406638.2019.1709212
Abstract: A series of 2-(6-phenyl-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazin-3-yl)-2,3-dihydrophthalazine-1,4-diones (4a–4o) have been synthesized via a one-pot multi-component reaction. The reaction of 4-am... read more here.
Keywords: thiadiazin dihydrophthalazine; pot multi; dihydrophthalazine diones; triazolo thiadiazin ... See more keywords
Synthesis, X-ray Crystal Structure, Anticancer, Hirshfeld Surface Analysis, DFT, TD-DFT, ADMET, and Molecular Docking of 3-Phenyl-1,2,4-triazolo[3,4-h]-13,4-thiaza-11-crown-4
Sign Up to like & getrecommendations! Published in 2023 at "Molecules"
DOI: 10.3390/molecules28073166
Abstract: In this work, we describe the synthesis of new macrocycles derived from 3-phenyl-1,2,4-triazole-5-thione 1 in a heterogeneous medium using liquid–solid phase transfer catalysis (PTC) conditions. The structures of the two compounds (3 and 4) isolated… read more here.
Keywords: hirshfeld surface; thiaza crown; triazolo thiaza; dft ... See more keywords