Bioproduction of natural phenethyl acetate, phenylacetic acid, ethyl phenylacetate, and phenethyl phenylacetate from renewable feedstock.
Sign Up to like & getrecommendations! Published in 2022 at "ChemSusChem"
DOI: 10.1002/cssc.202102645
Abstract: Natural phenethyl acetate (PEA), phenylacetic acid (PAA), ethyl phenylacetate (Et-PA), and phenethyl phenylacetate (PE-PA) are highly wanted aroma chemicals, but with limited availability and high price. Here we developed green, sustainable, and efficient bioproduction of… read more here.
Keywords: phenethyl acetate; phenethyl; phenylacetate; ethyl phenylacetate ... See more keywords
Population Pharmacokinetic Analysis to Assist Dose Selection of the l-Ornithine Salt of Phenylacetic Acid
Sign Up to like & getrecommendations! Published in 2021 at "Clinical Pharmacokinetics"
DOI: 10.1007/s40262-021-01075-1
Abstract: l-Ornithine phenylacetate is an intravenous formulation of the l-ornithine salt of phenylacetic acid under development for the treatment of hepatic encephalopathy. Very limited clinical data in patients are available, with a phase II study in… read more here.
Keywords: population pharmacokinetic; dose selection; phenylacetic acid; ornithine ... See more keywords
γ-Cyclodextrin-phenylacetic acid mesh as a drug trap.
Sign Up to like & getrecommendations! Published in 2018 at "Carbohydrate polymers"
DOI: 10.1016/j.carbpol.2017.12.078
Abstract: In this study, we developed a nanoporous biodegradable mesh, bioinspired by the spider web, which is prepared via electrospinning using γ-cyclodextrin (γ-CD) conjugated with phenylacetic acid (PA), named γ-CDP. The resulting γ-CDP has a microfibrous… read more here.
Keywords: drug; cyclodextrin phenylacetic; drug trap; phenylacetic acid ... See more keywords
One-Step Formation of Pharmaceuticals Having a Phenylacetic Acid Core Using Water Microdroplets.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.3c00773
Abstract: The properties of water microdroplets strikingly differ from bulk water. Using room-temperature water microdroplets, we find that toluene can react with CO2 to form phenylacetic acid in one step without any catalyst with negative high… read more here.
Keywords: water; one step; acid; water microdroplets ... See more keywords
The Phenylacetic Acid Catabolic Pathway Regulates Antibiotic and Oxidative Stress Responses in Acinetobacter
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DOI: 10.1128/mbio.01863-21
Abstract: Acinetobacter baumannii causes a wide range of infections that are difficult to treat due to increasing rates of multidrug resistance; however, the mechanisms that this pathogen uses to respond to stress are poorly understood. Here,… read more here.
Keywords: stress; acinetobacter; paa; pathway ... See more keywords
An improved method for the synthesis of phenylacetic acid derivatives via carbonylation
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Chemical Research"
DOI: 10.1177/1747519819876202
Abstract: 2,4-Dichlorophenylacetic acid is synthesized in high yield via the carbonylation of 2,4-dichlorobenzyl chloride, and various experimental conditions are evaluated. Xylene, bistriphenylphosphine palladium dichloride, tetraethylammonium chloride and sodium hydroxide in solution are added to the reaction… read more here.
Keywords: carbonylation; via carbonylation; improved method; phenylacetic acid ... See more keywords