Codelivery of BCL2 and MCL1 Inhibitors Enabled by Phenylboronic Acid‐Functionalized Polypeptide Nanovehicles for Synergetic and Potent Therapy of Acute Myeloid Leukemia
Sign Up to like & getrecommendations! Published in 2023 at "Advanced Science"
DOI: 10.1002/advs.202204866
Abstract: Acute myeloid leukemia (AML) is the most refractory hematologic malignancy characterized by acute onset, rapid progression, and high recurrence rate. Here, codelivery of BCL2 (ABT199) and MCL1 (TW37) inhibitors using phenylboronic acid‐functionalized polypeptide nanovehicles to… read more here.
Keywords: bcl2; mcl1; phenylboronic acid; acid functionalized ... See more keywords
Homocoupling of Phenylboronic Acid using Atomically Dispersed Gold on Carbon Catalysts: Catalyst Evolution Before Reaction
Sign Up to like & getrecommendations! Published in 2018 at "ChemCatChem"
DOI: 10.1002/cctc.201701840
Abstract: Coupling reactions to form new C−C bonds are extensively used in industrial synthetic processes. Gold has been shown to be an active catalyst for such reactions; however, conflicting reports exist as to whether cationic Au… read more here.
Keywords: carbon; homocoupling phenylboronic; atomically dispersed; phenylboronic acid ... See more keywords
Phenylboronic acid as a novel agent for controlling plant pathogenic bacteria.
Sign Up to like & getrecommendations! Published in 2022 at "Pest management science"
DOI: 10.1002/ps.6872
Abstract: BACKGROUND Phenylboronic acid (PBA) is an environmentally nontoxic substance with antimicrobial activity. Due to increasing ecological limitations in phytopharmacy and considering the development of resistance of phytopathogenic bacteria to available antibacterial agents, here we explore… read more here.
Keywords: pba; pathogenic bacteria; phenylboronic acid; agent ... See more keywords
Structural effect of fluorophore on phenylboronic acid fluorophore/cyclodextrin complex for selective glucose recognition
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers of Chemical Science and Engineering"
DOI: 10.1007/s11705-019-1851-y
Abstract: Based on the design of the fluorescent site of a fluorescent probe, we have created a unique system that changes its twisting response to sugar. Two probes were synthesized, in which phenylboronic acid and two… read more here.
Keywords: fluorophore; response; fluorescence; cyclodextrin ... See more keywords
Assembly of silica nanoparticles based on stimuli-responsive covalent bonding between glycopolymers and poly(phenylboronic acid)s
Sign Up to like & getrecommendations! Published in 2020 at "European Polymer Journal"
DOI: 10.1016/j.eurpolymj.2020.109888
Abstract: Abstract Covalent bonding between boronic acid and cis-diols is widely used to prepare stimuli-responsive nano materials. Herein, we report a kind of extremely rapid formation of boronate esters between glycopolymers and poly(phenylboronic acid)s for the… read more here.
Keywords: covalent bonding; phenylboronic acid; stimuli responsive; silica nanoparticles ... See more keywords
Fluorescent behaviors and reaction mechanism of 10-hydroxybenzo[h]quinolone on the detection of phenylboronic acid
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Luminescence"
DOI: 10.1016/j.jlumin.2020.117224
Abstract: Abstract The fluorescent behaviors and reaction mechanism of 10-hydroxybenzo[h]quinolone (HBQ) on the detection of phenylboronic acid (PBA) have been theoretical studied. The potential curves scan of HBQ in the first single (S1) excited state indicates… read more here.
Keywords: fluorescent behaviors; mechanism; phenylboronic acid; behaviors reaction ... See more keywords
Stimuli-responsive multifunctional micelles of ABC vs. ACB triblock terpolymers using reversible covalent bonding of phenylboronic acid: controlled synthesis, self-assembly and model drug release
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Molecular Liquids"
DOI: 10.1016/j.molliq.2021.116528
Abstract: Abstract We report the synthesis and self-assembly of well-defined, amphiphilic, biodegradable and glucose- and pH-responsive ABC and ACB triblock terpolymer multifunctional micelles in aqueous media using blocks consisting of poly(ethylene oxide) (PEO), poly(e-caprolactone) (PCL), and… read more here.
Keywords: abc acb; drug; acb triblock; multifunctional micelles ... See more keywords
Pyrolysis mechanism of phenylboronic acid modified phenolic resin
Sign Up to like & getrecommendations! Published in 2021 at "Polymer Degradation and Stability"
DOI: 10.1016/j.polymdegradstab.2021.109672
Abstract: Abstract Phenylboronic acid (PBA) modified phenolic resin (PBPR) is one of the most important phenolic resins (PR) due to its good processability and high char yield. However, the pyrolysis mechanisms of PR and PBPR still… read more here.
Keywords: modified phenolic; char yield; pyrolysis; phenylboronic acid ... See more keywords
New tetrahedral boron heterobicycles: Cyclocondensation of phenylboronic acid with β-keto butanoic acid N-acyl hydrazones
Sign Up to like & getrecommendations! Published in 2017 at "Tetrahedron Letters"
DOI: 10.1016/j.tetlet.2016.12.060
Abstract: Abstract A series of 4-phenyl-2-aryl-8-methyl-6-oxo-7-phenylhydrazo-2H,4H,6H,7H,8H[1,3,4,2]-oxadiazaborolo[2,3-b][1,3,2]oxazaborines were prepared in high yields via the reaction of phenylboronic acid with various N-acylhydrazones of 3-keto-2-(2′-phenylhydrazono) butanoic acid in the presence of 4 A molecular sieves. These derivatives represent a novel… read more here.
Keywords: boron; tetrahedral boron; butanoic acid; phenylboronic acid ... See more keywords
Micelle-Embedded Layer-by-Layer Coating with Catechol and Phenylboronic Acid for Tunable Drug Loading, Sustained Release, Mild Tissue Response, and Selective Cell Fate for Re-endothelialization.
Sign Up to like & getrecommendations! Published in 2019 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.9b01253
Abstract: Tunable/sustained drug loading/releasing are of significance in addressing low cytotoxicity, long-term performance, and localized mild healing response in biomedical applications. With an ingenious design, a self-healing sandwiched layer-by-layer (LBL) coating was constructed by using chitosan/heparin… read more here.
Keywords: drug loading; response; layer; phenylboronic acid ... See more keywords
Phenylboronic Acid Modification Augments the Lysosome Escape and Antitumor Efficacy of a Cylindrical Polymer Brush-Based Prodrug.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.1c09741
Abstract: Timely lysosome escape is of paramount importance for endocytosed nanomedicines to avoid premature degradation under the acidic and hydrolytic conditions in lysosomes. Herein, we report an exciting finding that phenylboronic acid (PBA) modification can greatly… read more here.
Keywords: based prodrug; phenylboronic acid; cylindrical polymer; escape ... See more keywords