Regioselective transmonocyanoacetylation of o-phenylenediamine derivatives: simple and efficient synthesis of 2-cyanomethylbenzimidazole derivatives
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DOI: 10.1007/s13738-018-1541-6
Abstract: A simple and efficient method for the regioselective transmonocyanoacetylation of o-phenylenediamine derivatives was developed using 1-cyanoacetyl-3,5-dimethylpyrazole as a cyanoacetylating agent. This method provided operationally simple and efficient access to a series of N-(2-aminophenyl)-2-cyanoacetamide derivatives under… read more here.
Keywords: cyanomethylbenzimidazole derivatives; regioselective transmonocyanoacetylation; transmonocyanoacetylation phenylenediamine; phenylenediamine derivatives ... See more keywords