One Pot Asymmetric Synthesis of (R)‐Phenylglycinol from Racemic Styrene Oxide via Cascade Biocatalysis
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DOI: 10.1002/cctc.201900492
Abstract: (R)‐Phenylglycinol is an important chiral building block for pharmaceutical and fine chemical industry, and its efficient synthesis from cheap and commercially available starting materials is challenging and highly desirable. Herein, a new three‐step one‐pot cascade… read more here.
Keywords: styrene oxide; racemic styrene; cascade; phenylglycinol ... See more keywords
Optimization of the Lipase-Catalyzed Selective Amidation of Phenylglycinol
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Bioengineering and Biotechnology"
DOI: 10.3389/fbioe.2019.00486
Abstract: Ceramides and their analogs have a regulatory effect on inflammatory cytokines expression. It was found that a kind of ceramides analog synthesized from phenylglycinol could inhibit the production of cytokine TNF-α. However, two active hydrogen… read more here.
Keywords: regio selectivity; phenylglycinol; lipase; amidation ... See more keywords