Switching of Regioselectivity in a Perfluorohexyl Iodide Mediated Synthesis of Phenylimidazo[1,2‐a]pyridines
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DOI: 10.1002/ejoc.201601586
Abstract: An array of 3-phenylimidazo[1,2-a]pyridines has been synthesized via perfluorohexyl iodide-mediated coupling of 2-aminopyridines and phenylacetylenes. In-situ iodination of the terminal alkyne by perfluorohexyl iodide reverses the polarity by generating a transient electrophilic iodoalkyne, altering the… read more here.
Keywords: perfluorohexyl; phenylimidazo pyridines; regioselectivity; iodide mediated ... See more keywords
Rapid and efficient one-pot microwave-assisted synthesis of 2-phenylimidazo[1,2-a]pyridines and 2-phenylimidazo[1,2-a]quinoline in water–PEG-400
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DOI: 10.1080/00397911.2016.1262040
Abstract: ABSTRACT An effective, expeditious, environmentally benign one-pot synthesis of 2-phenylimidazo[1,2-a]pyridines and 2-phenylimidazo[1,2-a]quinoline from easily available starting materials as aromatic carbonyl compound, 2-amino pyridine, succinamide, and in situ generated α-iodo acetophenone in combination with green solvent… read more here.
Keywords: phenylimidazo pyridines; synthesis phenylimidazo; peg 400; phenylimidazo quinoline ... See more keywords