Discovery of 4-nitro-3-phenylisoxazole derivatives as potent antibacterial agents derived from the studies of [3 + 2] cycloaddition
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DOI: 10.1039/d2ra05009a
Abstract: Polysubstituted phenylisoxazoles were designed and synthesized to discover new antibacterial agents via [3 + 2] cycloaddition. Thirty-five compounds with a phenylisoxazole scaffold were characterized by NMR, HRMS, and X-ray techniques. After being evaluated against Xanthomonas… read more here.
Keywords: derivatives potent; potent antibacterial; phenylisoxazole derivatives; antibacterial agents ... See more keywords