Efficient Oxidative Resolution of 1-Phenylphosphol-2-Ene and Diels-Alder Synthesis of Enantiopure Bicyclic and Tricyclic P-Stereogenic C-P Heterocycles
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DOI: 10.3390/sym12030346
Abstract: 1-Phenylphosphol-2-ene 1-oxide is effectively resolved by L-menthyl bromoacetate to afford both SP and RP enantiomers of 1-phenylphosphol-2-ene 1-oxide on a multigram scale. The resolved 1-phenylphosphol-2-ene oxide has been found to undergo face-selective and endo-selective cycloadditions… read more here.
Keywords: ene oxide; stereogenic heterocycles; ene; phenylphosphol ene ... See more keywords