Clinical characteristics and outcomes of SDHB-related pheochromocytoma and paraganglioma in children and adolescents
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Cancer Research and Clinical Oncology"
DOI: 10.1007/s00432-020-03138-5
Abstract: Pheochromocytomas/paragangliomas (PHEOs/PGLs) are rare in children with only a few SDHB mutation-related cases. Previous studies on children were conducted in small cohorts. This large set of pediatric patients provides robust data in the evaluation of… read more here.
Keywords: years post; age; pheo pgl; age years ... See more keywords
Phase 2 trial of Lu-177-DOTATATE in inoperable pheochromocytoma/paraganglioma.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2019.37.15_suppl.tps4159
Abstract: TPS4159 Background: Pheochromocytoma/paraganglioma (PHEO/PGL) is a rare malignancy that arises from chromaffin cells of typically the adrenal medulla but can also be of extra-adrenal origin. These tumors produce excessive catecholamines such as epinephrine and norepinephrine… read more here.
Keywords: dotatate; pheo pgl; pheochromocytoma paraganglioma; 177 dotatate ... See more keywords
SAT-311 Retroperitoneal Paraganglioma in a Patient Post-Fontan: The Association
Sign Up to like & getrecommendations! Published in 2019 at "Journal of the Endocrine Society"
DOI: 10.1210/js.2019-sat-311
Abstract: Abstract Background: Pheochromocytomas and paragangliomas (PHEO/PGL) are catecholamine producing tumors of the autonomous nervous system that arise from the chromaffin cells in the adrenal medulla or extra-adrenal paraganglionic tissue. About 40% of these tumors are… read more here.
Keywords: heart disease; pheo pgl; paraganglioma; pheo ... See more keywords
A Novel Liquid Biopsy (NETest) identifies Paragangliomas and Pheochromocytomas with High Accuracy.
Sign Up to like & getrecommendations! Published in 2021 at "Endocrine-related cancer"
DOI: 10.1530/erc-21-0216
Abstract: Pheochromocytomas and paragangliomas (PHEOs/PGLs) represent diagnostically challenging and complex neuroendocrine tumors (NETs). Current biomarker tests for PHEOs/PGLs are technically complex or limited. We assessed the diagnostic utility of a NET-specific 51-marker gene blood assay (NETest)… read more here.
Keywords: pheo pgl; cluster; novel liquid; accuracy ... See more keywords
Tumour microenvironment in pheochromocytoma and paraganglioma
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Endocrinology"
DOI: 10.3389/fendo.2023.1137456
Abstract: Pheochromocytomas and Paragangliomas (Pheo/PGL) are rare catecholamine-producing tumours derived from adrenal medulla or from the extra-adrenal paraganglia respectively. Around 10–15% of Pheo/PGL develop metastatic forms and have a poor prognosis with a 37% of mortality… read more here.
Keywords: tumour microenvironment; microenvironment pheochromocytoma; pgl; metastatic forms ... See more keywords
Clinical, Diagnostic, and Treatment Characteristics of SDHA-Related Metastatic Pheochromocytoma and Paraganglioma
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2019.00053
Abstract: Background: Pheochromocytoma and paraganglioma (PHEO/PGL) are rare neuroendocrine tumors which may cause potentially life-threatening complications, with about a third of cases found to harbor specific gene mutations. Thus, early diagnosis, treatment, and meticulous monitoring are… read more here.
Keywords: treatment; pheo pgl; sdha related; related metastatic ... See more keywords