First Evidence of Pheomelanin-UVA-Driven Synthesis of Pummerer’s Ketones by Peroxidase-Mediated Oxidative Coupling of Substituted Phenols
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DOI: 10.1021/acsomega.2c06584
Abstract: Photoexcitation of pheomelanin produces high-energy singlet oxygen and the superoxide anion, which are reactive species in damage of cellular targets. In principle, these species can be involved in processes of synthetic utility when adequate experimental… read more here.
Keywords: pummerer ketones; coupling substituted; peroxidase; pheomelanin ... See more keywords
Changes in melanocyte RNA and DNA methylation favour pheomelanin synthesis and may avoid systemic oxidative stress after dietary cysteine supplementation in birds
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DOI: 10.1111/mec.15024
Abstract: Cysteine plays essential biological roles, but excessive amounts produce cellular oxidative stress. Cysteine metabolism is mainly mediated by the enzymes cysteine dioxygenase and γ‐glutamylcysteine synthetase, respectively coded by the genes CDO1 and GCLC. Here we… read more here.
Keywords: cysteine; pheomelanin; dietary cysteine; synthesis ... See more keywords