Partially hydrolyzed guar gum upregulates heat shock protein 27 in intestinal Caco-2 cells and mouse intestine via mTOR and ERK signaling.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of the science of food and agriculture"
DOI: 10.1002/jsfa.12551
Abstract: BACKGROUND The intestinal epithelium acts as a barrier against harmful luminal materials, thus, preventing intestinal diseases, and maintaining intestinal health. Heat shock protein 27 (HSP27) promotes intestinal epithelial integrity under physiological and stressed conditions. The… read more here.
Keywords: hsp27 expression; caco cells; phgg; intestinal caco ... See more keywords
Does the interval from tumour surgery to radiotherapy influence survival in paediatric high grade glioma?
Sign Up to like & getrecommendations! Published in 2018 at "Strahlentherapie Und Onkologie"
DOI: 10.1007/s00066-018-1260-z
Abstract: PurposePaediatric high grade glioma (pHGG) are rare. Following maximum safe resection, children >3 years with HGG receive radiotherapy as standard of care. Whether the interval from tumour surgery to radiotherapy (ISRT) influences survival is disputed in… read more here.
Keywords: phgg; radiotherapy; survival; grade glioma ... See more keywords
Partially Hydrolyzed Guar Gum Alleviates Small Intestinal Mucosal Damage after Massive Small Bowel Resection along with Changes in the Intestinal Microbiota.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of pediatric surgery"
DOI: 10.1016/j.jpedsurg.2019.08.048
Abstract: PURPOSE Short bowel syndrome is associated with intestinal mucosal inflammation and microbial dysbiosis, leading to intractable complications. Partially hydrolyzed guar gum (PHGG) has trophic and anti-inflammatory effects on the intestine. We investigated whether PHGG ameliorates… read more here.
Keywords: mucosal damage; phgg; intestinal mucosal; small intestinal ... See more keywords
MODL-31. RADIATION-DERIVED TREATMENT-RESISTANT PDX AND CELL CULTURE MODELS RECAPITULATE THE CHARACTERISTICS OF MATCHED PRIMARY/RECURRENT PEDIATRIC HIGH-GRADE GLIOMA
Sign Up to like & getrecommendations! Published in 2020 at "Neuro-Oncology"
DOI: 10.1093/neuonc/noaa222.604
Abstract: Abstract BACKGROUND Pediatric high-grade glioma (pHGG) is the most common cause of childhood cancer death. Recurrence after therapy is a major challenge, since recurrent pHGG proliferates aggressively and resists therapy. We developed and validated preclinical… read more here.
Keywords: nes fdr; primary recurrent; phgg; matched primary ... See more keywords
TMOD-09. A PATIENT-DERIVED XENOGRAFT MODEL MIMICKING RECURRENT PEDIATRIC MALIGNANT GLIOMA.
Sign Up to like & getrecommendations! Published in 2017 at "Neuro-oncology"
DOI: 10.1093/neuonc/nox083.208
Abstract: Abstract BACKGROUND: Pediatric high grade glioma (pHGG) is a devastating cancer of the central nervous system. The prognosis of this most malignant form of brain tumor remains poor, largely due to the inherent resistance of… read more here.
Keywords: glioma; phgg; xenograft model; oncology ... See more keywords
Partially Hydrolyzed Guar Gum Suppresses the Development of Sarcopenic Obesity
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DOI: 10.3390/nu14061157
Abstract: Partially hydrolyzed guar gum (PHGG) is a soluble dietary fiber derived through controlled enzymatic hydrolysis of guar gum, a highly viscous galactomannan derived from the seeds of Cyamopsis tetragonoloba. Here, we examined the therapeutic potential… read more here.
Keywords: guar gum; phgg; sarcopenic obesity;